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Study · Not a test of the peptide alone · 2012

2 results

Cost-effectiveness analysis of degarelix for advanced hormone-dependent prostate cancer.

Lu L, Peters J, Roome C, Stein K

BJU international23 Aug 2011Cited by 19 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  1. 01Computer modelNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn silicoOther

    In a metastatic prostate cancer model, degarelix versus triptorelin plus antiandrogen had an ICER of £59,000 per QALY gained.

    In plain wordsIn a prostate cancer model, degarelix versus triptorelin plus antiandrogen cost £59,000 per additional quality-adjusted life year.

    Outcome
    Not applicableIncremental cost-effectiveness ratio
    Study

    n: not reported in source

    decision analytic model with a decision tree and Markov model
    Comparator
    degarelix
    Outcome group
    Cost-effectiveness · Cancer

    Measurements

    ICER
    59,000 £ per QALY gained
    degarelix versus triptorelin plus antiandrogen

    Source sentences

    Summary
    In the base-case analysis, the incremental cost-effectiveness ratio (ICER) for degarelix vs triptorelin plus antiandrogen was £59,000 per QALY gained.
    3 context sentences
    Summary · context
    We developed a decision analytic model based on a clinical trial and literature review.
    Summary · context
    The two interventions evaluated were: (i) monthly injection of degarelix and (ii) 3-monthly triptorelin therapy plus short-term flutamide, cyproterone or bicalutamide treatment.
    Summary · context
    The base-case analysis assumed patients present with asymptomatic metastatic prostate cancer.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  2. 02Computer modelNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn silicoOther

    In the prostate cancer model, results were most sensitive to significant adverse event rates with triptorelin plus antiandrogen.

    In plain wordsIn a prostate cancer model, significant side effect rates with triptorelin plus antiandrogen had the largest effect on results.

    Outcome
    Not applicableSensitivity to adverse events
    Study

    n: not reported in source

    decision analytic model with a decision tree and Markov model
    Comparator
    degarelix
    Outcome group
    Cost-effectiveness · Cancer

    Source sentences

    Summary
    The model was most sensitive to the rate of significant adverse events in the triptorelin plus antiandrogen group.
    3 context sentences
    Summary · context
    We developed a decision analytic model based on a clinical trial and literature review.
    Summary · context
    The two interventions evaluated were: (i) monthly injection of degarelix and (ii) 3-monthly triptorelin therapy plus short-term flutamide, cyproterone or bicalutamide treatment.
    Summary · context
    The base-case analysis assumed patients present with asymptomatic metastatic prostate cancer.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    27 Oct 2026, 16:34 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    22 Oct 2026, 02:26 UTC

    Study results updated

  3. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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