In mice, 0.15 nmol kisspeptin‑10 had no significant effect on total testosterone 60 min after injection.
In plain wordsIn mice, kisspeptin‑10 at 0.15 nmol did not significantly change total testosterone 60 minutes after injection.
- Peptide
- Kisspeptin-10
- Outcome
- No significant changeTotal testosterone at 60 min
- Study
mousen: not reported in source
Mice- Outcome group
- Sex hormones and fertility · Endocrine and hormones
- Studied dose
- 0.15 nmol · peripheral · 60 min postinjectionAs given in this study (mouse).
Measurements
- Dose
- 0.15 nmol
- KP-10
Source sentences
In addition, 60 min postinjection, 0.15 nmol [dY](1)KP-10 significantly increased total testosterone levels in mice whereas the same dose of KP-10 had no significant effect.
1 context sentence(design, population, supporting numbers)
Those analogs that bound with relatively high affinity to KISS1R were tested for ability to stimulate ERK1/2 phosphorylation in vitro and for their ability to stimulate the HPG axis in vivo.