Trial · Interventional
RecruitingPhase 2Registry dataBPC 157 for Acute Hamstring Muscle Strain Repair
Short name BPC-HAMSTR
Overview
- Status
- Recruiting
- Phase
- Phase 2
- Enrollment
- 120 participants (estimated)
- Sponsor
- Hudson Biotech · Industry
- Design
- Randomized · Quadruple masking
- Countries
1 country
China
- Start
- 2 Feb 2026
- Primary completion
- 14 Feb 2027 (estimated)
- Completion
- 17 Feb 2028 (estimated)
- First posted
- 27 Feb 2026
- Last update posted
- 27 Feb 2026
- Conditions
- Hamstring Muscle Strain · Skeletal Muscle Injury
Timeline
1 trial · 1 ongoing
- Completed
- Ongoing
- Not yet recruiting
- Stopped
- Estimated dates (est.)
- Results posted
- Ph 2
Registry summary
Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.
This randomized, double-blind, placebo-controlled Phase 2 study evaluates whether pentadecapeptide BPC 157 (BPC-157), an investigational peptide, can speed structural healing and functional recovery after an acute grade II hamstring muscle strain. Participants will receive BPC 157 or placebo for 14 days in addition to a standardized rehabilitation program. The co-primary endpoints are time to return to unrestricted sport and change in MRI-assessed injury volume at Day 14.
Interventions
- Pentadecapeptide BPC 157Drug
- PlaceboDrug
Arms2
Experimental
Arm 1: Experimental - BPC 157
Participants receive investigational pentadecapeptide BPC 157 plus standardized rehabilitation.
Experimental
Arm 2: Placebo Comparator - Placebo
Participants receive matching placebo plus standardized rehabilitation.
Primary outcomes2
Outcomes the sponsor listed as primary.
Time to return to unrestricted sport participation (days)
Time frame · 8 Weeks
Registry description
defined as clearance by a blinded sports medicine clinician and completion of a standardized functional performance battery without pain-limited stopping.
Change from baseline to Day 14 in MRI-assessed hamstring injury volume (cm^3), measured by blinded central radiology review.
Time frame · 14 Days
Secondary outcomes(3)
Change in pain during activity on a 0-10 Numeric Rating Scale (NRS; 0 = no pain, 10 = worst pain).
Time frame · 56 Days
Hamstring strength limb symmetry index (LSI) by isokinetic dynamometry
Time frame · 56 Days
Change in Lower Extremity Functional Scale (LEFS; 0-80, higher scores indicate better function)
Time frame · 56 Days
Posted results
Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.
No results are posted for this trial.
A trial that is still running, or that stopped early, may post results later.
Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works
Studies0
Studies that cite this trial.
No study cites this trial.
Eligibility
Who could join, as posted.
- Sex
- All
- Age
- from 18 Years up to 45 Years
- Healthy volunteers
- Not accepted
Inclusion and exclusion criteria, as posted
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