Indexing hint: Randomized controlled trial · 2026
Treatment With 9-mg Mazdutide for Weight Reduction in Chinese Adults With Obesity: The GLORY-2 Randomized Clinical Trial.
Gao et al. 2026JAMA
PMID 42251595DOI 10.1001/jama.2026.8142PUB-42251595
Trial · Interventional
Status unknownPhase 3Registry dataChina
1 trial
Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.
This is a multicenter, randomized, double-blind, placebo-controlled Phase 3 clinical study evaluating the efficacy and safety of IBI362 9 mg in obese subjects. Subjects will be randomly assigned to IBI362 9 mg and placebo groups. All study treatment will be administered once-weekly and subcutaneously. The entire trial cycle includes a 2-week screening period, a 60-week double-blind treatment period, and a 12-week drug withdrawal follow-up period after the end of treatment.
Placebo comparator
Placebo
Experimental
IBI362
Outcomes the sponsor listed as primary.
Percent Change from Baseline in Body Weight
Time frame · Week 60
Proportion of Participants who Achieve ≥5% Body Weight Reduction
Time frame · Week 60
Proportion of Participants who Achieve ≥10% Body Weight Reduction
Time frame · Week 60
Proportion of Participants who Achieve ≥15% Body Weight Reduction
Time frame · Week 60
Proportion of Participants who Achieve ≥20% Body Weight Reduction
Time frame · Week 60
Change from Baseline in Waist Circumference
Time frame · Week 60
Change from Baseline in Systolic Blood Pressure
Time frame · Week 60
Percent Change from Baseline in Triglycerides
Time frame · Week 60
Percent Change from Baseline in non-high-density lipoprotein cholesteroal
Time frame · Week 60
Percent Change from Baseline in low-density lipoprotein cholesterol
Time frame · Week 60
Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.
No results are posted for this trial.
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Studies that cite this trial.
1 study on this page
Indexing hint: Randomized controlled trial · 2026
Gao et al. 2026JAMA
PMID 42251595DOI 10.1001/jama.2026.8142PUB-42251595
Who could join, as posted.
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