Adding Desmopressin to Tamsulosin for Treatment of BPH

NCTNCT05945420Other idMS.22.12.2245

Open at ClinicalTrials.govAsk about this trial

Overview

Status: Status unknown
Phase: Phase 4
Enrollment: 160 participants (estimated)
Sponsor: Mansoura University · Other
Design: Randomized · Open label (no masking)
Countries: 1 country
Egypt
Start: 20 Jul 2023 (estimated)
Primary completion: 10 Jan 2024 (estimated)
Completion: 10 Feb 2024 (estimated)
First posted: 14 Jul 2023
Last update posted: 14 Jul 2023
Conditions: Nocturnal Polyurea in Patients With BPH

Timeline

1 trial

Completed
Ongoing
Not yet recruiting
Stopped
Estimated dates (est.)
Results posted

202320242025

Ph 4
Adding Desmopressin to Tamsulosin for Treatment of BPH
NCT05945420
est. 20 Jul 2023 to est. 10 Feb 2024

Registry summary

Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.

In this study investigators will add desmopressin for treatment of patients with benign prostatic hyperplasia and nocturnal polyurea

Interventions

Desmopressin AcetateDrug
PlaceboDrug

Arms2

Active comparator
Desmopressin arm
This arm will receive tamsulosin and desmopressin
Placebo comparator
Placebo arm
This arm will receive tamsulosin and placepo

Primary outcomes1

Outcomes the sponsor listed as primary.

Change of symptoms and nocturia disappears or improve
Time frame · Follow up for 6 months
Registry description
Investigators will compare symptoms in the pretreatment period and follow up symptoms following treatment and record the outcome

Posted results

Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.

No results are posted for this trial.

A trial that is still running, or that stopped early, may post results later.

Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works

Studies0

Studies that cite this trial.

No study cites this trial.

Eligibility

Who could join, as posted.

Sex: Male
Age: from 50 Years up to 80 Years
Healthy volunteers: Accepted

Inclusion and exclusion criteria, as posted

Inclusion Criteria: Men with BPH Age more than 50years Patients with nocturia (2voids per night or More) Patients with nocturnal polyurea (urine volume More than 33%of urine allover the day) IPSS more than 12 Obstructed flow curve Post voiding residual less than 150 Exclusion Criteria: * men with BPH with : Acute urine retention Neurogenic bladder dysfunction Cardiovascular disease Hyponatremia Urethral stricture Bladder calculi Prostate cancer

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