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Trial · Interventional

CompletedNot applicableRegistry data

Oxytocin Administration and Emotion Recognition Abilities in Adults Reporting Adverse Childhood Experiences

NCTNCT03335085 (opens ClinicalTrials.gov in a new tab)Other idKU 2479/3-1
Open at ClinicalTrials.govAsk about this trial

Overview

Status
Completed
Phase
Not applicable
Enrollment
80 participants (actual)
Sponsor
Ruhr University of Bochum · Other
Design
Not randomized · Double masking
Countries
Not stated
Start
1 Jul 2011
Primary completion
23 Mar 2013
Completion
5 Nov 2013
First posted
7 Nov 2017
Last update posted
7 Nov 2017
Conditions
Healthy

Timeline

1 trial · 1 completed

  • Completed
  • Ongoing
  • Not yet recruiting
  • Stopped
  • Estimated dates (est.)
  • Results posted
2011201220132014
  1. N/A

    Oxytocin Administration and Emotion Recognition Abilities in Adults Reporting Adverse Childhood Experiences

    NCT03335085

    1 Jul 2011 to 5 Nov 2013

Registry summary

Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.

This study evaluates whether intranasal administration of a single dose of oxytocin improves the ability to recognize emotional states. In a cross-over design, half of the participants first received oxytocin, the other half first received placebo.

Interventions

  • OxytocinDrug
  • PlaceboOther

Arms2

  • Active comparator

    Oxytocin

    Single dose of intranasally administered 24 IU of Oxytocin (Syntocinon-Spray Novartis, Switzerland)

  • Placebo comparator

    Placebo

    All ingredients except for oxytocin.

Primary outcomes2

Outcomes the sponsor listed as primary.

  1. Reading the Mind in the Eyes Test

    Time frame · 45 minutes post-dose

    Registry description

    Requires participants to infer complex mental states fromthe eye region

  2. Gradual Emotion Recognition Test

    Time frame · 50 minutes post-dose

    Registry description

    Requires participants to swiftly and accurately detect basic emotions form naturalistic, animated stimuli.

Posted results

Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.

No results are posted for this trial.

Completed trials do not always post results.

Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works

Studies1

Studies that cite this trial.

Studies with results

1 study on this page

Indexing hint: Clinical trial · 2019

3 results

Oxytocin administration and emotion recognition abilities in adults with a history of childhood adversity.

Schwaiger et al. 2019Psychoneuroendocrinologycited by 24

PMID 30189345DOI 10.1016/j.psyneuen.2018.08.025PUB-30189345

Full text at the publisher3 results
Publisher pageSee results (3)

Eligibility

Who could join, as posted.

Sex
All
Age
from 18 Years up to 60 Years
Healthy volunteers
Accepted
Inclusion and exclusion criteria, as posted
Inclusion Criteria: • presence of moderate to severe experiences of childhood adversity (early adversity group) Exclusion Criteria: * Acute psychiatric disorders and personality disorders or psychiatric disorders within the last 12 months * Pregnancy

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