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Trial · Interventional

WithdrawnEarly phase 1Registry data

Role of Oxytocin in Telling and Detecting Lies

Overview

Status
Withdrawn
Phase
Early phase 1
Enrollment
0 participants (actual)
Sponsor
University of Texas at Austin · Other
Design
Randomized · Triple masking
Countries
Not stated
Start
Jan 2016
Primary completion
Apr 2016
Completion
Apr 2016
First posted
11 Feb 2015 (estimated)
Last update posted
13 Jun 2016 (estimated)
Conditions
Dyssocial Behavior

Timeline

1 trial · 1 stopped early

  • Completed
  • Ongoing
  • Not yet recruiting
  • Stopped
  • Estimated dates (est.)
  • Results posted
20162017
  1. Ph Early 1

    Role of Oxytocin in Telling and Detecting Lies

    NCT02361177

    Jan 2016 to Apr 2016

    Withdrawn

Registry summary

Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.

The investigators are interested in the impact of intranasal oxytocin in unethical behavior.

Interventions

  • OxytocinDrug

Arms2

  • Experimental

    oxytocin

    Intranasal 24 IU oxytocin self-administration.

  • Placebo comparator

    placebo

    Intranasal placebo. 125 mg of 0.5% cholorobutanol to 50 ml saline, with approximately 5 pH. The solution will then be sterilized using a 0.22 micron filter.

Primary outcomes1

Outcomes the sponsor listed as primary.

  1. Unethical behavior

    Time frame · 130 minutes

    Registry description

    To measure unethical behavior, we will calculate whether participants took more money than they actually earned on a problem-solving task.

Posted results

Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.

No results are posted for this trial.

A trial that is still running, or that stopped early, may post results later.

Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works

Studies1

Studies that cite this trial.

Studies with results

1 study on this page

Indexing hint: Clinical trial · 2005

3 results

Oxytocin increases trust in humans.

Kosfeld et al. 2005Naturecited by 1,701

PMID 15931222DOI 10.1038/nature03701PUB-15931222

Full text at the publisher3 results

Eligibility

Who could join, as posted.

Sex
Male
Age
from 18 Years up to 30 Years
Healthy volunteers
Accepted
Inclusion and exclusion criteria, as posted
Inclusion Criteria: * Male Exclusion Criteria: * \_\_\_\_\_ \_\_\_\_\_BP \> 130/85, HRT \> 95 (can be included at discretion of study physician/designee) * \_\_\_\_\_History of seizures * \_\_\_\_\_Neurological Disorder * \_\_\_\_\_Current psychiatric disorder * \_\_\_\_\_Previous psychiatric disorder (can be included at discretion of PI) * Date last episode (if \> 1 year, include; if \<1 year, at discretion of PI) * \_\_\_\_\_Current use of psychoactive drugs * \_\_\_\_\_Previous use of psychoactive drugs (can be included at discretion of PI) \_\_\_\_\_Date last medicated\_\_\_\_\_ \_\_\_\_\_Type of medication\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ * \_\_\_\_\_Current use of anticoagulants * \_\_\_\_\_Current use of corticosteroids * \_\_\_\_\_Previous head trauma (can be included at discretion of PI) * \_\_\_\_\_Alcoholism or substance abuse * \_\_\_\_\_Carcinoma of the breast or prostate * \_\_\_\_\_Renal or Hepatic diseases * \_\_\_\_\_Chronic lung diseases * \_\_\_\_\_Cancer * \_\_\_\_\_Liver problems * \_\_\_\_\_Hypertension/Cardiac diseases * \_\_\_\_\_Cardiovascular Disease * \_\_\_\_\_Nephritis * \_\_\_\_\_Diabetes (use of insulin) /Obesity * \_\_\_\_\_Endocrine disease or malignancy * \_\_\_\_\_Asthma (can be included as discretion of study physician/designee, if episodes are infrequent, nonmedicated, and no active problems at time of study) * Medication * Frequency of episodes\_\_\_\_ \_\_\_\_\_Date of last episode\_\_\_\_\_ * \_\_\_\_\_Migraines(can be included as discretion of study physician/designee, if episodes are infrequent, nonmedicated, and no active problems at time of study) * Medication \_\_\_\_\_Frequency of migraines\_\_\_\_\_ \_\_\_\_\_Date of last migraine\_\_\_\_\_ * \_\_\_\_\_High levels of physical contact with women or children

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