Indexing hint: Clinical trial · 2018
Pharmacokinetics and tolerability of semaglutide in people with hepatic impairment.
Jensen et al. 2018Diabetes, obesity & metabolismcited by 58
PMID 29205786PMC5873441DOI 10.1111/dom.13186PUB-29205786
Trial · Interventional
CompletedPhase 1Registry dataPoland, Slovakia
1 trial · 1 completed
Investigating the Pharmacokinetics, Safety and Tolerability After a Single Subcutaneous Injection of Semaglutide in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function
NCT022108717 Aug 2014 to 3 Jun 2015
Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.
This trial is conducted in Europe. The aim of this trial is to investigate the pharmacokinetics (the exposure of the trial drug in the body), safety and tolerability after a single injection of semaglutide in subjects with mild, moderate or severe hepatic impairment compared to subjects with normal hepatic function.
Experimental
Normal hepatic function
Experimental
Mild hepatic impairment
Experimental
Moderate hepatic impairment
Experimental
Severe hepatic impairment
Outcomes the sponsor listed as primary.
Area under the semaglutide plasma concentration-time curve
Time frame · Day 1 - day 36
Maximum observed semaglutide plasma concentration
Time frame · Day 1 - day 36
Number of treatment emergent adverse events (TEAEs)
Time frame · Day 1 - day 36
Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.
No results are posted for this trial.
Completed trials do not always post results.
Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works
Studies that cite this trial.
1 study on this page
Indexing hint: Clinical trial · 2018
Jensen et al. 2018Diabetes, obesity & metabolismcited by 58
PMID 29205786PMC5873441DOI 10.1111/dom.13186PUB-29205786
Who could join, as posted.
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