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Trial · Interventional

CompletedPhase 1Registry data

Oxytocin, Couple Interaction and Wound Healing

NCTNCT01594775 (opens ClinicalTrials.gov in a new tab)Other idKEK-ZH-NR: 2009-0063
Open at ClinicalTrials.govAsk about this trial

Overview

Status
Completed
Phase
Phase 1
Enrollment
160 participants (actual)
Sponsor
University of Zurich · Other
Design
Randomized · Double masking
Countries
1 country

Switzerland

Start
Oct 2011
Primary completion
Oct 2013
Completion
Oct 2013
First posted
9 May 2012 (estimated)
Last update posted
25 Feb 2014 (estimated)
Conditions
Healthy Volunteers

Timeline

1 trial · 1 completed

  • Completed
  • Ongoing
  • Not yet recruiting
  • Stopped
  • Estimated dates (est.)
  • Results posted
2011201220132014
  1. Ph 1

    Oxytocin, Couple Interaction and Wound Healing

    NCT01594775

    Oct 2011 to Oct 2013

Registry summary

Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.

effects of intranasal oxytocin and couple interaction on wound healing. * Trial with medicinal product

Interventions

  • Syntocinon (Oxytocin) nasal sprayDrug
  • PlaceboDrug

Arms2

  • Active comparator

    nasal spray

  • Placebo comparator

    Placebo

Primary outcomes1

Outcomes the sponsor listed as primary.

  1. wound size

    Time frame · seven days

    Registry description

    wound healing process within seven days after wounding

Posted results

Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.

No results are posted for this trial.

Completed trials do not always post results.

Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works

Studies3

Studies that cite this trial.

Studies with results

1 study on this page

Indexing hint: Randomized controlled trial · 2025

Minimal couple intervention to improve psychobiological stress resilience.

Aguilar-Raab et al. 2025British journal of health psychologycited by 2

PMID 40356464PMC12070146DOI 10.1111/bjhp.12799PUB-40356464

CC BY
Download PDF

Indexing hint: Randomized controlled trial · 2022

4 results

The Effect of Intranasal Oxytocin on the Association Between Couple Interaction and Sleep: A Placebo-Controlled Study.

Doerr et al. 2022Psychosomatic medicinecited by 5

PMID 35472193DOI 10.1097/psy.0000000000001091PUB-35472193

Full text at the publisher4 results
Publisher pageSee results (4)

More studies

1 study on this page

Indexing hint: Randomized controlled trial · 2026

Corrected

Intranasal Oxytocin and Physical Intimacy for Dermatological Wound Healing and Neuroendocrine Stress: A Randomized Clinical Trial.

Schneider et al. 2026JAMA psychiatrycited by 4

PMID 41222549PMC12613093DOI 10.1001/jamapsychiatry.2025.3705PUB-41222549

CC BY
Download PDFRead the notice

Eligibility

Who could join, as posted.

Sex
All
Age
from 21 Years up to 45 Years
Healthy volunteers
Not accepted
Inclusion and exclusion criteria, as posted
Inclusion criteria: * healthy heterosexual couples * in a stable relationship since \> 1 year Exclusion criteria: pregnancy * breast feeding * heavy smoking (\> 5 cigarettes/d) * extensive skin disease * artificial UV irradiation during \< 3 months before study inclusion

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