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Study · Other design · 2018

2 results

The use of hormonal strategies to improve the safety of in vitro fertilisation

Clarke S

Imperial College London1 Jan 2018

DOI10.25560/78820 (opens in a new tab)PepBankPUB-95323196
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanOther designEfficacy outcome

    In women at high risk of OHSS having IVF, more patients reached a clinically acceptable mature oocyte yield with two kisspeptin‑54 injections than with one.

    In plain wordsIn women at high risk of ovarian overstimulation having IVF, more reached a good mature egg yield with two kisspeptin‑54 injections than with one.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    IncreaseClinically acceptable mature oocyte yield with two kisspeptin-54 injections
    Study

    n: not reported in source

    Comparator
    Single injection of kisspeptin-54
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    I demonstrate that greater numbers of patients achieve a clinically acceptable mature oocyte yield in those receiving two injections of kisspeptin-54 without an increase in rates of OHSS.
    1 context sentence
    Summary · context
    In this thesis, I therefore first explore whether the addition of a second injection of kisspeptin-54 10hrs after the first during IVF treatment results in prolonged LH action in a population of women at high risk of OHSS.
  2. 02HumanOther designSafety outcome

    In women at high risk of OHSS having IVF, two kisspeptin‑54 injections did not increase the rate of OHSS compared with one.

    In plain wordsIn women at high risk of ovarian overstimulation having IVF, two kisspeptin‑54 injections did not raise overstimulation rates compared with one.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    No significant changeOHSS rate with two kisspeptin-54 injections
    Study

    n: not reported in source

    Comparator
    Single injection of kisspeptin-54
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    I demonstrate that greater numbers of patients achieve a clinically acceptable mature oocyte yield in those receiving two injections of kisspeptin-54 without an increase in rates of OHSS.
    1 context sentence
    Summary · context
    In this thesis, I therefore first explore whether the addition of a second injection of kisspeptin-54 10hrs after the first during IVF treatment results in prolonged LH action in a population of women at high risk of OHSS.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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