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Study · Animal study (in vivo) · equus africanus asinus · 2020

3 results

Comparative Efficacy of Histrelin Acetate and hCG for Inducing Ovulation in Brazilian Northeastern Jennies (Equus africanus asinus)

Oliveira SN, Segabinazzi LGTM, Canuto L, Lisboa FP, Medrado FE, Dell’Aqua JA, Aguiar AJA, Papa FO

Journal of equine veterinary science1 Sept 2020

PepBankPUB-92965390
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Summary

The text of this summary is not shown here, because the article license does not allow reuse.

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In jennies, histrelin shortened the prostaglandin-to-ovulation interval versus saline control (145.2 ± 34.6 versus 220.0 ± 41.8 hours, P < .05).

    In plain wordsIn jennies, histrelin shortened the time from prostaglandin administration to ovulation compared with saline control.

    Peptide
    Histrelin
    Outcome
    DecreaseProstaglandin-to-ovulation interval
    Study

    Equus africanus asinusn: not reported in source

    Brazilian Northeastern jennies
    Comparator
    saline control
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    250 μgAs given in this study (Equus africanus asinus).

    Source sentences

    Summary
    The interval between prostaglandin administration and ovulation was lower (P < .05) in jennies from the G1 (145.2 ± 34.6 hours) and G2 (147.4 ± 27.3 hours) groups compared with the control cycle (220.0 ± 41.8 hours).
    1 context sentence
    Summary · context
    Thirty cycles of ten jennies were randomly assigned in one of the three groups: G0 (control group), saline; G1, 250 μg of histrelin acetate; G2, 2500 IU of hCG.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In jennies, histrelin shortened the inducer-to-ovulation interval versus control (41.15 ± 3.5 versus 81.8 ± 28.8 hours, P < .05).

    In plain wordsIn jennies, histrelin shortened the time from the ovulation-inducing agent to ovulation compared with control.

    Peptide
    Histrelin
    Outcome
    DecreaseInducer-to-ovulation interval
    Study

    Equus africanus asinusn: not reported in source

    Brazilian Northeastern jennies
    Comparator
    saline control
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    250 μgAs given in this study (Equus africanus asinus).

    Source sentences

    Summary
    Both treatments (G1, 41.15 ± 3.5 hours; G2, 37.8 ± 2.5 hours) also reduced (P < .05) the interval that jennies took to ovulate after the administration of the ovulation-inducing agent compared with the control (81.8 ± 28.8 hours).
    1 context sentence
    Summary · context
    Thirty cycles of ten jennies were randomly assigned in one of the three groups: G0 (control group), saline; G1, 250 μg of histrelin acetate; G2, 2500 IU of hCG.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    All histrelin-treated jennies ovulated within 48 hours, whereas all saline controls ovulated later.

    In plain wordsIn jennies, all histrelin-treated animals ovulated within 48 hours, whereas all saline controls ovulated later.

    Peptide
    Histrelin
    Outcome
    IncreaseOvulation within 48 hours
    Study

    Equus africanus asinusn: not reported in source

    Brazilian Northeastern jennies
    Comparator
    saline control
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    250 μgAs given in this study (Equus africanus asinus).

    Source sentences

    Summary
    All jennies from G1 and G2 ovulated up to 48 hours after ovulation induction, whereas 100% of jennies in the control cycle ovulated later (>48 hours from the administration of saline).
    1 context sentence
    Summary · context
    Thirty cycles of ten jennies were randomly assigned in one of the three groups: G0 (control group), saline; G1, 250 μg of histrelin acetate; G2, 2500 IU of hCG.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

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