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Study · In vitro (cells) · monopterus albus · 2021

2 results

Regulation of Melanocortin-5 Receptor Pharmacology by Two Isoforms of MRAP2 in Ricefield Eel (Monopterus albus)

Liu T, Yi T, Yang D, Tao Y

Journal of the Endocrine Society3 May 2021

PMCIDPMC8090599 (opens in a new tab)PepBankPUB-90417729
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In cells expressing ricefield eel MC5R (maMC5R), NDP-MSH bound to the receptor.

    In plain wordsIn cells carrying the ricefield eel MC5R receptor, NDP-MSH bound to the receptor.

    Peptide
    Melanotan I (afamelanotide)
    Outcome
    Not applicableBinding to ricefield eel MC5R
    Study

    Monopterus albusn: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Three agonists, [Nle4, D-Phe7]-alpha-melanocyte stimulating hormone (NDP-MSH), alpha-MSH, and adrenocorticotropin (ACTH), could bind to maMC5R and induce intracellular cAMP production dose-dependently.
  2. 02LabIn vitro (cells)Activity measurement

    In cells expressing ricefield eel MC5R (maMC5R), NDP-MSH induced intracellular cAMP production in a dose-dependent way.

    In plain wordsIn cells carrying the ricefield eel MC5R receptor, NDP-MSH raised cAMP production, and more NDP-MSH gave more cAMP.

    Peptide
    Melanotan I (afamelanotide)
    Outcome
    IncreasecAMP production via ricefield eel MC5R
    Study

    Monopterus albusn: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Three agonists, [Nle4, D-Phe7]-alpha-melanocyte stimulating hormone (NDP-MSH), alpha-MSH, and adrenocorticotropin (ACTH), could bind to maMC5R and induce intracellular cAMP production dose-dependently.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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