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Study · Not a test of the peptide alone · 2026

1 result

Mitochondrial-derived peptides (MDPs) activated by physical exercise as therapeutic targets for metabolic disorders: A systematic review.

Ayubi N, Wibawa JC, Kurnaz M, Komaini A

Physiology international25 Aug 2026

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, MOTS-c was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking MOTS-c.

  1. 01HumanNot a test of MOTS-c aloneSystematic reviewOther

    In a systematic review of nine studies, most reported a trend toward higher levels of mitochondrial-derived peptides (a group that includes MOTS‑c) after exercise; the authors urge caution.

    In plain wordsIn a review of nine studies, most found a trend to higher levels of the body's own mitochondrial-derived peptides after exercise.

    Peptide
    MOTS-c
    Outcome
    IncreaseMDP levels after exercise
    Study

    n = 9

    Outcome group
    Exercise and physical function · Metabolic and weight

    Source sentences

    Summary
    Of the nine studies included in this systematic review, most reported a trend toward increased MDP levels after exercise.
    1 context sentence
    Summary · context
    Mitochondrial-derived peptides (MDPs), such as humanin and MOTS-c, play a role in regulating energy balance and cellular stress responses.

    In this study, MOTS-c was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MOTS-c.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    13 Oct 2026, 16:31 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    10 Oct 2026, 10:21 UTC

    Study results updated

  3. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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