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Study · Not a test of the peptide alone · 2026

9 results

Fabrication and characterization of biocompatible BPC-157 based chitosan hydrogel.

Arunim, Dagar M, Solanki M, Sarita, Mishra R, Gulliya S, Bajpai S

3 Biotech6 Jul 2026

PMID42555375 (opens in a new tab)DOI10.1007/s13205-026-04951-4 (opens in a new tab)PepBankPUB-42555375
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study9

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone9

In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking BPC-157.

  1. 01LabNot a test of BPC-157 aloneIn vitro (cells)Activity measurement

    The CH/BPC hydrogel inhibited Escherichia coli by up to 45.9%.

    In plain wordsIn lab tests, the BPC‑157 chitosan gel inhibited E. coli growth.

    Peptide
    BPC-157
    Outcome
    DecreaseInhibition of E. coli
    Study

    Escherichia colin: not reported in source

    Bacterial culture exposed to CH/BPC hydrogel
    Outcome group
    Infection and antimicrobial activity · Infection

    Measurements

    Inhibition
    45.9%
    E. coli

    Source sentences

    Summary
    In addition, the CH/BPC hydrogel demonstrated potent antibacterial efficacy, achieving up to 45.9% (Escherichia coli) and 65.0% (Staphylococcus aureus) inhibition.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  2. 02LabNot a test of BPC-157 aloneIn vitro (cells)Activity measurement

    The CH/BPC hydrogel inhibited Staphylococcus aureus by up to 65.0%.

    In plain wordsIn lab tests, the BPC‑157 chitosan gel inhibited S. aureus growth.

    Peptide
    BPC-157
    Outcome
    DecreaseInhibition of S. aureus
    Study

    Staphylococcus aureusn: not reported in source

    Bacterial culture exposed to CH/BPC hydrogel
    Outcome group
    Infection and antimicrobial activity · Infection

    Measurements

    Inhibition
    65%
    S. aureus

    Source sentences

    Summary
    In addition, the CH/BPC hydrogel demonstrated potent antibacterial efficacy, achieving up to 45.9% (Escherichia coli) and 65.0% (Staphylococcus aureus) inhibition.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  3. 03LabNot a test of BPC-157 aloneIn vitro (cells)Safety outcome

    The CH/BPC hydrogel had a hemolysis rate below 5%, indicating acceptable hemocompatibility.

    In plain wordsIn lab tests, the BPC‑157 chitosan gel damaged few blood cells.

    Peptide
    BPC-157
    Outcome
    No significant changeHemolysis rate
    Study

    n: not reported in source

    Red blood cells exposed to CH/BPC hydrogel
    Outcome group
    Adverse events · Pharmacology

    Measurements

    Hemolysis rate
    < 5%
    CH/BPC hydrogel

    Source sentences

    Summary
    The fabricated hydrogel also showed a hemolysis rate of less than 5%, indicating acceptable hemocompatibility.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  4. 04LabNot a test of BPC-157 aloneIn vitro (cell-free)Other

    A chitosan hydrogel containing BPC‑157 (CH/BPC) showed a porous structure on electron microscopy.

    In plain wordsIn lab tests, a chitosan gel containing BPC‑157 had a porous structure.

    Peptide
    BPC-157
    Outcome
    Not applicableHydrogel porous structure
    Study

    n: not reported in source

    CH/BPC chitosan composite hydrogel
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    The formulation exhibited a porous structure, analyzed through scanning electron microscopy (SEM) and transmission electron microscopy (TEM).
    1 context sentence
    Summary · context
    In this study, CH/BPC composite hydrogel was fabricated and characterized for their physicochemical properties.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  5. 05LabNot a test of BPC-157 aloneIn vitro (cell-free)Other

    FTIR showed hydrogen bonding between BPC‑157 and the chitosan backbone, indicating peptide incorporation in the hydrogel matrix.

    In plain wordsIn lab tests, BPC‑157 bonded to the chitosan gel material, showing it was built into the gel.

    Peptide
    BPC-157
    Outcome
    Not applicableHydrogen bonding between BPC-157 and chitosan
    Study

    n: not reported in source

    CH/BPC chitosan composite hydrogel
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    Fourier-transform infrared spectroscopy (FTIR) showed the presence of hydrogen bond between BPC-157 peptide and chitosan backbone, indicating successful peptide incorporation within the hydrogel matrix.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  6. 06LabNot a test of BPC-157 aloneIn vitro (cell-free)Other

    The CH/BPC hydrogel had a balanced water vapor transmission rate of 2,270 ± 35 g/m2/day.

    In plain wordsIn lab tests, the BPC‑157 chitosan gel let water vapour pass at a balanced rate.

    Peptide
    BPC-157
    Outcome
    Not applicableWater vapor transmission rate
    Study

    n: not reported in source

    CH/BPC chitosan composite hydrogel
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    The composite hydrogel exhibited a balanced water vapor transmission rate (2,270 ± 35 g/m2 /day), along with remarkable properties of injectability, self-healing capability, and adhesiveness.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  7. 07LabNot a test of BPC-157 aloneIn vitro (cell-free)Other

    The CH/BPC hydrogel showed injectability, self-healing capability and adhesiveness.

    In plain wordsIn lab tests, the BPC‑157 chitosan gel could be injected, healed itself and stuck to surfaces.

    Peptide
    BPC-157
    Outcome
    Not applicableInjectability, self-healing and adhesiveness
    Study

    n: not reported in source

    CH/BPC chitosan composite hydrogel
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    along with remarkable properties of injectability, self-healing capability, and adhesiveness.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  8. 08LabNot a test of BPC-157 aloneIn vitro (cell-free)Pharmacokinetics

    The CH/BPC hydrogel encapsulated BPC‑157 with 98.9 ± 0.8% efficiency.

    In plain wordsIn lab tests, the chitosan gel held almost all of the BPC‑157 loaded into it.

    Peptide
    BPC-157
    Outcome
    Not applicableBPC-157 encapsulation efficiency
    Study

    n: not reported in source

    CH/BPC chitosan composite hydrogel
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    Encapsulation
    98.9%
    CH/BPC hydrogel

    Source sentences

    Summary
    Furthermore, the hydrogel demonstrated excellent encapsulation (98.9 ± 0.8%) of BPC-157, with release profile of 81.2 ± 2.9% within 24 h.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

  9. 09LabNot a test of BPC-157 aloneIn vitro (cell-free)Pharmacokinetics

    The CH/BPC hydrogel released 81.2 ± 2.9% of BPC‑157 within 24 h.

    In plain wordsIn lab tests, the chitosan gel released most of its BPC‑157 within a day.

    Peptide
    BPC-157
    Outcome
    Not applicableBPC-157 release within 24 h
    Study

    n: not reported in source

    CH/BPC chitosan composite hydrogel
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    Release at 24 h
    81.2%
    CH/BPC hydrogel

    Source sentences

    Summary
    Furthermore, the hydrogel demonstrated excellent encapsulation (98.9 ± 0.8%) of BPC-157, with release profile of 81.2 ± 2.9% within 24 h.

    In this study, BPC-157 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking BPC-157.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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