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Study · Case report or series · n = 1 · 2026

2 results

Acute Nutritional Axonal Neuropathy in the Setting of Semaglutide-Associated Gastrointestinal Intolerance: A Case Report.

Cohan CJ, Townley L, Ortega E

Case reports in neurology1 Jan 2026

PMID42549476 (opens in a new tab)PMCIDPMC13432944 (opens in a new tab)DOI10.1159/000552961 (opens in a new tab)PepBankPUB-42549476
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanCase report or seriesSafety outcome

    In a 65-year-old woman with type 2 diabetes and obesity, months of semaglutide therapy were followed by persistent nausea and vomiting and a 120-pound weight loss.

    In plain wordsIn one woman with type 2 diabetes, months of semaglutide were followed by lasting nausea and vomiting and a 120-pound weight loss.

    Peptide
    Semaglutide
    Outcome
    Not applicableWeight loss with persistent nausea and vomiting
    Study

    n = 1

    Outcome group
    Adverse events · Gastrointestinal
    Studied dose
    Dose not stated · monthsAs given in this study (human).

    Measurements

    Weight loss
    120 pound
    case patient

    Source sentences

    Summary
    and a 120-pound weight loss after months of semaglutide therapy with persistent nausea and vomiting.
    1 context sentence
    Summary · context
    A 65-year-old woman with type 2 diabetes and obesity presented with profound weakness, cranial nerve deficits, dysphagia, and a 120-pound weight loss after months of semaglutide therapy with persistent nausea and vomiting.
  2. 02HumanCase report or seriesSafety outcome

    In a 65-year-old woman with type 2 diabetes, severe sensory-predominant polyneuropathy from nutritional deficiencies occurred in the setting of semaglutide-related malnutrition.

    In plain wordsIn one woman, severe nerve damage from vitamin deficiencies occurred after semaglutide-related malnutrition.

    Peptide
    Semaglutide
    Outcome
    Not applicableSevere sensorimotor polyneuropathy (acute nutritional axonal neuropathy)
    Study

    n = 1

    Outcome group
    Adverse events · Nervous system and cognition
    Studied dose
    Dose not stated · monthsAs given in this study (human).

    Source sentences

    Summary
    The aim of the study was to report a unique case of severe sensorimotor polyneuropathy due to acute nutritional axonal neuropathy (ANAN) associated with thiamine and other vitamin deficiencies in the setting of semaglutide-related malnutrition, emphasizing early recognition and intervention to preve…
    2 context sentences
    Summary · context
    Electromyography demonstrated absent sensory responses and mild motor slowing, consistent with severe sensory-predominant polyneuropathy.
    Summary · context
    A 65-year-old woman with type 2 diabetes and obesity presented with profound weakness, cranial nerve deficits, dysphagia, and a 120-pound weight loss after months of semaglutide therapy with persistent nausea and vomiting.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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