In a liver transplant recipient with recurrent MASH, a multimodal metabolic intervention that included semaglutide reduced steatosis to 30%.
In plain wordsIn one liver transplant patient, a treatment package that included semaglutide came with lower liver fat. The effect of semaglutide alone is unknown.
- Peptide
- Semaglutide
- Outcome
- DecreaseHepatic steatosis
- Study
n = 1
- Outcome group
- Liver fat and liver function · Liver
Measurements
- Steatosis
- 30%
- after intervention
Source sentences
Multimodal intervention, including semaglutide, resulted in histologic improvement (steatosis reduced to 30%, ballooning resolved) with sustained biochemical normalization.
1 context sentence(design, population, supporting numbers)
We present a 40-year-old woman with obesity and remote kidney transplant who underwent liver transplantation for MASH cirrhosis. At 10 weeks posttransplant, she developed acute cellular rejection and 68% steatosis, progressing to >95% steatohepatitis with F1 fibrosis within 6 days on corticosteroid treatment.
In this study, Semaglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Semaglutide.