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Study · Not a test of the peptide alone · 2026

2 results

Obesity Management Pharmacotherapies and Lifestyle Treatment for Pediatric Obesity Management: A Systematic Review and Network Meta-Analysis.

Wan KW, Lei EF, Liu Y, Taddese AA, Ip P, Torbahn G, Weghuber D, Huang WY, Tam BT

JAMA pediatrics1 Sept 2026Cited by 1 (Europe PMC)

PMID42329656 (opens in a new tab)DOI10.1001/jamapediatrics.2026.2248 (opens in a new tab)PepBankPUB-42329656
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Semaglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Semaglutide.

  1. 01HumanNot a test of Semaglutide aloneSystematic reviewEfficacy outcome

    In children and adolescents with obesity, the regimen of semaglutide plus counseling was associated with the largest BMI reduction in the network meta-analysis (mean difference -8.31), from a limited number of studies.

    In plain wordsIn children and teenagers with obesity, semaglutide combined with counseling was linked to the largest BMI drop, but few studies support this.

    Peptide
    Semaglutide
    Outcome
    DecreaseBMI change with semaglutide plus counseling
    Study

    n: not reported in source

    Analysis
    Primary
    Outcome group
    Body weight · Metabolic and weight

    Measurements

    BMI mean difference
    −8.31
    semaglutide plus counseling

    Source sentences

    Summary
    Semaglutide plus counseling was associated with the largest BMI reduction (mean difference, -8.31; 95% CI, -12.33 to -4.28)
    1 context sentence
    Summary · context
    Randomized clinical trials (RCTs) involving children and adolescents (aged 10-19 years) with obesity were selected.

    In this study, Semaglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Semaglutide.

  2. 02HumanNot a test of Semaglutide aloneSystematic reviewEfficacy outcome

    In children and adolescents with obesity, the regimen of semaglutide plus counseling was associated with the largest BMI z score reduction in the network meta-analysis (mean difference -1.80), from a limited number of studies.

    In plain wordsIn children and teenagers with obesity, semaglutide combined with counseling was linked to the largest drop in BMI z score, but few studies support this.

    Peptide
    Semaglutide
    Outcome
    DecreaseBMI z score change with semaglutide plus counseling
    Study

    n: not reported in source

    Analysis
    Primary
    Outcome group
    Body weight · Metabolic and weight

    Measurements

    BMI z score mean difference
    −1.8
    semaglutide plus counseling

    Source sentences

    Summary
    BMI z score reduction (mean difference, -1.80; 95% CI, -2.39 to -1.21), although this estimate was based on a limited number of studies
    1 context sentence
    Summary · context
    Randomized clinical trials (RCTs) involving children and adolescents (aged 10-19 years) with obesity were selected.

    In this study, Semaglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Semaglutide.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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