Skip to content

Study · Case report or series · n = 1 · 2026

3 results

Spontaneous Pneumomediastinum Associated with Semaglutide Therapy: A Case Report.

Diebold J, Gubler C, Murray FR

Case reports in gastroenterology1 Jan 2026

PMID42291462 (opens in a new tab)PMCIDPMC13263006 (opens in a new tab)DOI10.1159/000551669 (opens in a new tab)PepBankPUB-42291462
Read at sourcePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanCase report or seriesSafety outcome

    In a 26-year-old woman, spontaneous pneumomediastinum developed shortly after self-administered semaglutide bought online for weight loss.

    In plain wordsIn one young woman, air in the chest cavity developed soon after she used semaglutide bought online.

    Peptide
    Semaglutide
    Outcome
    IncreaseSpontaneous pneumomediastinum
    Study

    n = 1

    Outcome group
    Adverse events · Respiratory
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We report the case of a 26-year-old woman who developed SPM shortly after the self-administered use of semaglutide purchased online for weight loss.
    1 context sentence
    Summary · context
    Imaging revealed extensive pneumomediastinum and cervicothoracic emphysema.
  2. 02HumanCase report or seriesSafety outcome

    In a 26-year-old woman using self-administered semaglutide, the presentation included vomiting, chest and neck pain, and progressive facial swelling.

    In plain wordsIn one young woman using semaglutide bought online, vomiting, chest and neck pain, and facial swelling were reported.

    Peptide
    Semaglutide
    Outcome
    IncreaseVomiting, chest and neck pain, and facial swelling
    Study

    n = 1

    Outcome group
    Adverse events · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The patient presented with vomiting, chest and neck pain, and progressive facial swelling.
    1 context sentence
    Summary · context
    We report the case of a 26-year-old woman who developed SPM shortly after the self-administered use of semaglutide purchased online for weight loss.
  3. 03HumanCase report or seriesSafety outcome

    In a 26-year-old woman with spontaneous pneumomediastinum after self-administered semaglutide, conservative management led to spontaneous recovery.

    In plain wordsIn one young woman, recovery happened on its own with conservative management.

    Peptide
    Semaglutide
    Outcome
    DecreaseRecovery from pneumomediastinum
    Study

    n = 1

    Outcome group
    Adverse events · Respiratory
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The patient was managed conservatively with spontaneous recovery.
    1 context sentence
    Summary · context
    We report the case of a 26-year-old woman who developed SPM shortly after the self-administered use of semaglutide purchased online for weight loss.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.