In people with obesity, liraglutide and calorie restriction had no significant between-group interaction for pancreatic fat fraction (interaction p = 0.560).
In plain wordsIn people with obesity, liraglutide and calorie restriction did not differ significantly for pancreatic fat.
- Peptide
- Liraglutide
- Outcome
- No significant changePancreatic fat fraction
- Study
n = 46
- Comparator
- Calorie restricted diet
- Analysis
- Primary
- Outcome group
- Body composition · Metabolic and weight
- Studied dose
- Dose not stated · 24 weeksAs given in this study (human).
Source sentences
Both CRD (n = 23) and liraglutide (n = 23) demonstrated significant and comparable reductions in PFF (time effect: p < 0.001; interaction effect: p = 0.560).
3 context sentences(design, population, supporting numbers)
In this 24-week prospective nonrandomized study, participants with obesity received CRD or liraglutide.
Primary endpoint was the change in pancreatic fat fraction (PFF).
Secondary endpoints included changes in body weight, liver fat fraction (LFF), visceral fat area (VFA), and glycemic-related parameters.