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Study · Case report or series · n = 1 · 2026

1 result

Too much of a good thing.

Varghese D, Abdelsalam D, Ibrahim S, Lee AG, Bhatti MT

Survey of ophthalmology9 Jan 2026

PMID41520798 (opens in a new tab)DOI10.1016/j.survophthal.2026.01.001 (opens in a new tab)PepBankPUB-41520798
Publisher pagePubMedAsk about this study
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Summary

A 38-year-old man with poorly controlled type 2 diabetes mellitus and arterial hypertension on semaglutide presented with acute, painless, vision loss in the left eye. Ophthalmic examination revealed optic disc edema (ODE) in the left eye and optic disc pallor (ODP) in the right eye, accompanied by severe nonproliferative diabetic retinopathy and cystoid macular edema in both eyes. The combination of ODE in one eye and ODP in the fellow eye raised concern for the Foster Kennedy syndrome secondary to an intracranial mass; however, neuroimaging and systemic evaluation were unremarkable. Ultimately, it was decided the ODP was due to a prior unrecognized non-arteritic anterior ischemic optic neuropathy (NAION) event, and the ODE was the result of an acute NAION in the symptomatic fellow eye (i.e. pseudo-Foster Kennedy syndrome).
CC BYText from Europe PMC. Highlighted sentences are the source of results.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanCase report or seriesSafety outcome

    A 38-year-old man with type 2 diabetes taking semaglutide had acute NAION in the left eye with acute painless vision loss.

    In plain wordsA 38-year-old man with type 2 diabetes taking semaglutide lost vision in one eye from an optic nerve problem. Cause is unproven.

    Peptide
    Semaglutide
    Outcome
    Not applicableAcute non-arteritic anterior ischemic optic neuropathy (NAION)
    Study

    n = 1

    Outcome group
    Adverse events · Eye
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Ultimately, it was decided the ODP was due to a prior unrecognized non-arteritic anterior ischemic optic neuropathy (NAION) event, and the ODE was the result of an acute NAION in the symptomatic fellow eye (i.e. pseudo-Foster Kennedy syndrome).
    1 context sentence
    Summary · context
    A 38-year-old man with poorly controlled type 2 diabetes mellitus and arterial hypertension on semaglutide presented with acute, painless, vision loss in the left eye.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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