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Study · Non-randomized trial · 2025

4 results

Epitranscriptomic analysis reveals features of NAD-capped RNAs upon supplementation of nicotinamide mononucleotide in human.

Ge S, Liu Y, Li D, Han G, Niu K, Ju H, Zhou H, Liu R, Zhu Z, Liu N, Qu L

Experimental cell research8 Oct 2025Cited by 1 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialMechanism

    In humans, NMN supplementation increased NAD turnover.

    In plain wordsIn humans, NMN increased NAD turnover.

    Outcome
    IncreaseNAD turnover in humans
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We demonstrated that NMN supplementation increases NAD turnover coupled with a reduction in NAD-capped RNAs in both human and dog, revealing blood-derived NAD-RNAs as potential biomarkers sensitized to NMN exposure.
  2. 02HumanNon-randomized trialMechanism

    In humans, NMN supplementation reduced NAD-capped RNAs.

    In plain wordsIn humans, NMN reduced NAD-capped RNAs.

    Outcome
    DecreaseNAD-capped RNAs in humans
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We demonstrated that NMN supplementation increases NAD turnover coupled with a reduction in NAD-capped RNAs in both human and dog, revealing blood-derived NAD-RNAs as potential biomarkers sensitized to NMN exposure.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In dogs, NMN supplementation increased NAD turnover.

    In plain wordsIn dogs, NMN increased NAD turnover.

    Outcome
    IncreaseNAD turnover in dogs
    Study

    dogn: not reported in source

    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We demonstrated that NMN supplementation increases NAD turnover coupled with a reduction in NAD-capped RNAs in both human and dog, revealing blood-derived NAD-RNAs as potential biomarkers sensitized to NMN exposure.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In dogs, NMN supplementation reduced NAD-capped RNAs.

    In plain wordsIn dogs, NMN reduced NAD-capped RNAs.

    Outcome
    DecreaseNAD-capped RNAs in dogs
    Study

    dogn: not reported in source

    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We demonstrated that NMN supplementation increases NAD turnover coupled with a reduction in NAD-capped RNAs in both human and dog, revealing blood-derived NAD-RNAs as potential biomarkers sensitized to NMN exposure.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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