Across pharmacotherapy studies of metformin and liraglutide in reproductive-aged men with obesity, data were insufficient to draw clear conclusions about fertility outcomes.
In plain wordsFor reproductive-aged men with obesity, studies of metformin and liraglutide had too little data for clear fertility conclusions.
- Peptide
- Liraglutide
- Outcome
- Direction not reportedFertility outcomes
- Study
n: not reported in source
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
Source sentences
Pharmacotherapy (metformin and liraglutide) was assessed in five studies, including four quasi-experimental studies and one case report. There were insufficient data to draw clear conclusions regarding the impact of these agents on fertility outcomes.
2 context sentences(design, population, supporting numbers)
Studies of reproductive-aged men (18-50 years) who underwent an obesity intervention with established weight loss benefits and undertook repeated assessment of reproduction capacity (semen analysis, conception rates, assisted reproduction outcomes) before and after the intervention were included.
32 studies were included in the analysis, with one study assessing both lifestyle interventions and pharmacotherapy.
In this study, Liraglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Liraglutide.