Detection of Mitochondrial-Derived Peptide Humanin in Semen and Reproductive Tract of Caprine Along With Its Relation to Seasonality.

Chouksey S, Shukla SN, Dubey A, Soni Y, Mandal S, Chourasia A

Reproduction in domestic animals = Zuchthygiene1 Aug 2025

PMID40838645DOI10.1111/rda.70113PepBankPUB-40838645

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In bucks, immunofluorescence detected Humanin in elongated spermatids of the caput epididymis and in the interstitial space of the testes.
In plain wordsIn goats, the body's own Humanin was found in sperm-forming cells of the epididymis and in testis tissue.
Peptide
Humanin
Outcome
Not applicableHumanin in epididymis and testis
Study
goatn = 12
Sirohi and Barbari bucks
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Immunofluorescence examination of the male reproductive tract revealed the presence of green fluorescence, indicating humanin, in the elongated spermatids of the caput epididymis and the interstitial space of the testicles.
1 context sentence(design, population, supporting numbers)
Summary · context
A total of 12 bucks were selected, and an indirect immunofluorescence test was conducted to detect humanin using a commercially available anti-humanin antibody.
This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-4083864501
02AnimalEndogenous levelAnimal study (in vivo)Other
In bucks, Humanin was localised in the neck and acrosomal regions of ejaculated spermatozoa.
In plain wordsIn goats, the body's own Humanin was found in the neck and head cap of sperm cells.
Peptide
Humanin
Outcome
Not applicableHumanin localisation in ejaculated spermatozoa
Study
goatn = 12
Sirohi and Barbari bucks
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In ejaculated spermatozoa, humanin was localised in the neck and acrosomal regions.
1 context sentence(design, population, supporting numbers)
Summary · context
A total of 12 bucks were selected, and an indirect immunofluorescence test was conducted to detect humanin using a commercially available anti-humanin antibody.
This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-4083864502
03AnimalEndogenous levelAnimal study (in vivo)Other
In bucks, Humanin was also observed in the upper middle region of ejaculated spermatozoa.
In plain wordsIn goats, the body's own Humanin was also seen in the upper middle part of sperm cells.
Peptide
Humanin
Outcome
Not applicableHumanin in upper middle region of spermatozoa
Study
goatn = 12
Sirohi and Barbari bucks
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Humanin was also observed in the upper middle region of ejaculated spermatozoa.
1 context sentence(design, population, supporting numbers)
Summary · context
A total of 12 bucks were selected, and an indirect immunofluorescence test was conducted to detect humanin using a commercially available anti-humanin antibody.
This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-4083864503
04AnimalEndogenous levelAnimal study (in vivo)Other
In bucks, Humanin expression was stronger in the rainy season, with little fluorescence in summer and winter.
In plain wordsIn goats, natural Humanin levels in sperm were higher in the rainy season than in summer and winter.
Peptide
Humanin
Outcome
IncreaseSeasonal Humanin expression
Study
goatn = 12
Sirohi and Barbari bucks
Comparator
Summer and winter
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, during the rainy season, humanin expression was stronger or brighter, and throughout the summer and winter, there was little fluorescence.
1 context sentence(design, population, supporting numbers)
Summary · context
A total of 12 bucks were selected, and an indirect immunofluorescence test was conducted to detect humanin using a commercially available anti-humanin antibody.
This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-4083864504

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
13 Oct 2026, 21:44 UTC
Study results updated
Version 1
13 Oct 2026, 16:31 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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