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Study · Case report or series · n = 1 · 2025

3 results

Association of semaglutide use with depressive symptoms and suicidal behavior in a patient with type 2 diabetes: A case report.

Stojkovska A, Rus Prelog P, Kokalj Palandacic A

The Journal of international medical research12 Jul 2025Cited by 3 (Europe PMC)

PMID40652323 (opens in a new tab)PMCIDPMC12255853 (opens in a new tab)DOI10.1177/03000605251349393 (opens in a new tab)PepBankPUB-40652323
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanCase report or seriesSafety outcome

    In a man in his late 70s with type 2 diabetes and no psychiatric history, restlessness and depressive mood began around the time semaglutide was introduced.

    In plain wordsIn one older man with type 2 diabetes, restlessness and low mood began around the time semaglutide was started. One case cannot show cause.

    Peptide
    Semaglutide
    Outcome
    IncreaseRestlessness and depressive mood
    Study

    n = 1

    Outcome group
    Adverse events · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A month before his presentation, he reported restlessness and depressive mood without any apparent trigger. This period was consistent with the time of semaglutide introduction.
    1 context sentence
    Summary · context
    A man in his late 70s with type 2 diabetes and no history of psychiatric illness or cognitive deficits was admitted to our clinic after his first suicide attempt involving the impulsive ingestion of brush cleaner liquid.
  2. 02HumanCase report or seriesSafety outcome

    In a man in his late 70s with type 2 diabetes and no psychiatric history, a suicide attempt occurred about a month after restlessness and depressive mood began, around the time of semaglutide introduction.

    In plain wordsIn one older man with diabetes, a suicide attempt followed low mood that began when semaglutide was started. One case cannot show cause.

    Peptide
    Semaglutide
    Outcome
    IncreaseSuicide attempt
    Study

    n = 1

    Outcome group
    Adverse events · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A man in his late 70s with type 2 diabetes and no history of psychiatric illness or cognitive deficits was admitted to our clinic after his first suicide attempt involving the impulsive ingestion of brush cleaner liquid.
    1 context sentence
    Summary · context
    A month before his presentation, he reported restlessness and depressive mood without any apparent trigger. This period was consistent with the time of semaglutide introduction.
  3. 03HumanCase report or seriesSafety outcome

    In a man in his late 70s with type 2 diabetes, psychiatric symptoms improved after semaglutide was stopped.

    In plain wordsIn one older man with type 2 diabetes, mood symptoms improved after semaglutide was stopped.

    Peptide
    Semaglutide
    Outcome
    DecreasePsychiatric symptoms after semaglutide discontinuation
    Study

    n = 1

    Outcome group
    Adverse events · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    His psychiatric symptoms improved after semaglutide discontinuation.
    1 context sentence
    Summary · context
    A man in his late 70s with type 2 diabetes and no history of psychiatric illness or cognitive deficits was admitted to our clinic after his first suicide attempt involving the impulsive ingestion of brush cleaner liquid.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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