In a 14-year-old girl with familial partial lipodystrophy, satisfactory glycemic control was reported within two months after liraglutide was introduced following diet, metformin and insulin treatment; no isolated causal or numerical contrast was established.
In plain wordsIn one 14-year-old girl with familial partial lipodystrophy, satisfactory glycemic control was reported after liraglutide was added.
- Peptide
- Liraglutide
- Outcome
- Direction not reportedGlycemic control
- Study
n = 1
- Outcome group
- Glycemic control · Metabolic and weight
- Studied dose
- Dose not stated
Source sentences
The patient was initially treated with a diabetic diet, metformin, and insulin therapy, but glycemic control was only achieved after introducing liraglutide, resulting in satisfactory control within two months.
2 context sentences(design, population, supporting numbers)
The index patient is a 14-year-old girl, presenting with fat accumulation in the neck, loss of subcutaneous fat on the face, arms, legs, and trunk, and metabolic complications including diabetes mellitus with insulin resistance, hepatomegaly, and dyslipidemia.
Type 2 familial partial lipodystrophy (FPLD2), or Dunnigan syndrome, is a rare genetic disorder characterized by selective subcutaneous fat loss, metabolic complications, and insulin resistance due to LMNA gene mutations.