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Study · Case report or series · n = 4 · 2025

2 results

Anterior ischemic optic neuropathy in patients treated with semaglutide: report of four cases with a possible association.

Ahmadi H, Hamann S

BMC ophthalmology14 Mar 2025Cited by 17 (Europe PMC)

PMID40087651 (opens in a new tab)PMCIDPMC11908077 (opens in a new tab)DOI10.1186/s12886-025-03958-4 (opens in a new tab)PepBankPUB-40087651
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanCase report or seriesSafety outcome

    In four men, nonarteritic anterior ischemic optic neuropathy was diagnosed during semaglutide treatment, which lasted less than one year in three cases.

    In plain wordsIn four men, a type of optic nerve damage was found during semaglutide treatment. This does not show that semaglutide caused it.

    Peptide
    Semaglutide
    Outcome
    Not applicableNonarteritic anterior ischemic optic neuropathy during semaglutide treatment
    Study

    n = 4

    Outcome group
    Adverse events · Eye
    Studied dose
    Dose not stated · less than one year in three casesAs given in this study (human).

    Source sentences

    Summary
    Four male patients were diagnosed with NAION during semaglutide treatment, with treatment durations of less than one year in three cases.
    1 context sentence
    Summary · context
    This report presents four clinical cases and explores a possible association.
  2. 02HumanCase report or seriesSafety outcome

    In four men with optic neuropathy during semaglutide treatment, all had crowded optic discs and small Bruch's membrane opening diameters in three cases.

    In plain wordsIn four men with optic nerve damage during semaglutide treatment, the eyes had crowded optic discs. This does not show that semaglutide caused the damage.

    Peptide
    Semaglutide
    Outcome
    Not applicableSmall Bruch's membrane opening diameter in cases of optic neuropathy
    Study

    n = 4

    Outcome group
    Adverse events · Eye
    Studied dose
    Dose not stated

    Source sentences

    Summary
    All presented with significant optic disc edema and intraretinal fluid on optical coherence tomography, along with crowded optic disc and small Bruch's membrane opening diameters (< 1.4 mm in three cases).
    1 context sentence
    Summary · context
    This report presents four clinical cases and explores a possible association.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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