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Study · Case report or series · n = 1 · 2025

1 result

Semaglutide-Associated Ischemic Colitis in a Patient Without Traditional Risk Factors: A Case Report.

Sekhon S, Bacon J, Kahlon IS

Cureus10 Feb 2025Cited by 2 (Europe PMC)

PMID40084311 (opens in a new tab)PMCIDPMC11904261 (opens in a new tab)DOI10.7759/cureus.78832 (opens in a new tab)PepBankPUB-40084311
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Summary

This report describes the case of a 43-year-old female patient presenting with left lower quadrant pain and bloody diarrhea, initially managed as infectious colitis. Despite treatment, symptoms persisted, leading to repeat imaging showing mild pancolitis with colon mucosal hyperenhancement and wall thickening. Admission for intravenous hydration and subsequent colonoscopy revealed findings consistent with ischemic colitis. Semaglutide (Ozempic), which the patient had been taking, was discontinued, and symptoms resolved post discharge without semaglutide use for several months. This suggests a potential association between semaglutide and ischemic colitis in a patient without known risk factors. This case underscores the importance of considering medication-induced colitis in patients presenting with persistent gastrointestinal symptoms, particularly in the absence of typical risk factors.
CC BYText from Europe PMC. Highlighted sentences are the source of results.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanCase report or seriesSafety outcome

    In a 43-year-old woman without traditional risk factors, ischemic colitis occurred during semaglutide use and symptoms resolved after semaglutide was stopped.

    In plain wordsIn one woman without usual risk factors, bowel inflammation from poor blood flow occurred while she took semaglutide and cleared after she stopped it.

    Peptide
    Semaglutide
    Outcome
    Not applicableIschemic colitis during semaglutide use
    Study

    n = 1

    Outcome group
    Adverse events · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Semaglutide (Ozempic), which the patient had been taking, was discontinued, and symptoms resolved post discharge without semaglutide use for several months. This suggests a potential association between semaglutide and ischemic colitis in a patient without known risk factors.
    1 context sentence
    Summary · context
    This report describes the case of a 43-year-old female patient presenting with left lower quadrant pain and bloody diarrhea, initially managed as infectious colitis.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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