Skip to content

Study · Not a test of the peptide alone · 2025

1 result

CCN5 suppresses injury-induced vascular restenosis by inhibiting smooth muscle cell proliferation and facilitating endothelial repair via thymosin β4 and Cd9 pathway.

Zhang Q, Li H, Zhuang T, Xu L, Wu W, Pi J, Zhu P, Geng L, Duan Y, Xu J, Yue J, Liu X and 9 more

Show all authors

He C, Chen X, Ruan C, Zhuang S, Liu Z, Wang Y, Zhang L, Liu J, Zhang Y

European heart journal1 May 2025Cited by 11 (Europe PMC)

PMID39873228 (opens in a new tab)DOI10.1093/eurheartj/ehae911 (opens in a new tab)PepBankPUB-39873228
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In endothelial cells, mechanistic studies identified Tβ4 as a CCN5 interacting protein, and EC-CCN5 promoted injury repair through the Tβ4 cleavage product Ac-SDKP.

    In plain wordsIn endothelial cells, thymosin beta‑4 was found to bind the protein CCN5. Thymosin beta‑4 was not given as a treatment.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableTβ4 as CCN5 interacting protein
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Cardiovascular

    Source sentences

    Summary
    Mechanistic studies identified thymosin β4 (Tβ4) as a CCN5 interacting protein in ECs and EC-CCN5 promoted injury repair through Tβ4 cleavage product Ac-SDKP.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.