Palmitoyl copper peptide and acetyl tyrosine complex enhances melanin production in both A375 and B16 cell lines.

Hong M, Gui Y, Xu J, Zhao X, Jiang C, Zhao J, Xin X, Liu D, Tang X, Tang R, An F

Biochemical and biophysical research communications28 Nov 2024Cited by 2 (Europe PMC)

PMID39632290DOI10.1016/j.bbrc.2024.151060PepBankPUB-39632290

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHK-Cu.

01LabNot a test of GHK-Cu aloneIn vitro (cells)Efficacy outcome
In A375 human melanoma cells, the combination CP-AcT (palmitoyl copper peptide plus acetyl tyrosine) promoted melanin production.
In plain wordsIn human melanoma cells in the lab, a mix of palmitoyl copper peptide and acetyl tyrosine increased melanin production.
Peptide
GHK-Cu
Outcome
IncreaseMelanin production
Study
humann: not reported in source
A375 human melanoma cell line
Outcome group
Pigmentation · Skin and wound
Source sentences
Summary
The results indicate that the complex CP-AcT effectively promotes melanin production in both types of melanoma cells.
1 context sentence(design, population, supporting numbers)
Summary · context
In this study, we investigated the effects of a combination agent CP-AcT, composed of palmitoyl copper peptide (pal-GHK-Cu) and acetyl tyrosine (N-Acetyl-l-tyrosine), on melanin production in the human malignant melanoma cell line A375 and the mouse melanoma cell line B16.
In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.
Report a problemFND-3963229001
02LabNot a test of GHK-Cu aloneIn vitro (cells)Efficacy outcome
In B16 mouse melanoma cells, the combination CP-AcT (palmitoyl copper peptide plus acetyl tyrosine) promoted melanin production.
In plain wordsIn mouse melanoma cells in the lab, a mix of palmitoyl copper peptide and acetyl tyrosine increased melanin production.
Peptide
GHK-Cu
Outcome
IncreaseMelanin production
Study
mousen: not reported in source
B16 mouse melanoma cell line
Outcome group
Pigmentation · Skin and wound
Source sentences
Summary
The results indicate that the complex CP-AcT effectively promotes melanin production in both types of melanoma cells.
1 context sentence(design, population, supporting numbers)
Summary · context
In this study, we investigated the effects of a combination agent CP-AcT, composed of palmitoyl copper peptide (pal-GHK-Cu) and acetyl tyrosine (N-Acetyl-l-tyrosine), on melanin production in the human malignant melanoma cell line A375 and the mouse melanoma cell line B16.
In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.
Report a problemFND-3963229002

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 4Current
27 Oct 2026, 16:32 UTC
Study data updated · source update from Europe PMC
Version 3
10 Oct 2026, 08:19 UTC
Study results updated
Version 2
9 Oct 2026, 03:03 UTC
Study data updated · source update from Europe PMC
Version 1
9 Oct 2026, 02:56 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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