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Study · Not a test of the peptide alone · 2025

2 results

Weight Loss Induces Changes in Vitamin D Status in Women With Obesity But Not in Men: A Randomized Clinical Trial.

Holt R, Holt J, Jorsal MJ, Sandsdal RM, Jensen SBK, Byberg S, Juhl CR, Lundgren JR, Janus C, Stallknecht BM, Holst JJ, Juul A, Madsbad S, Jensen MB, Torekov SS

The Journal of clinical endocrinology and metabolism1 Jul 2025Cited by 8 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Liraglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Liraglutide.

  1. 01HumanNot a test of Liraglutide aloneObservational studyOther

    In women with obesity in the pooled liraglutide/exercise/placebo trial, further weight loss was linked to higher serum 25(OH)D than weight regain (14 nmol/L; 95% CI 6-22; P = .001).

    In plain wordsIn women with obesity in the mixed-intervention trial including liraglutide, further weight loss was linked to higher vitamin D than weight regain.

    Outcome
    IncreaseSerum 25-hydroxyvitamin D by further weight-loss status
    Study

    n: not reported in source

    Comparator
    Women regaining weight
    Outcome group
    Metabolic pathways and metabolomics · Endocrine and hormones

    Measurements

    25-hydroxyvitamin D difference
    14 nmol/L
    further weight loss versus regain; 95% CI 6-22; P = .001; pooled treatment arms

    Source sentences

    Summary
    Women who experienced a further weight loss during the 52 weeks of intervention had an increase in serum 25(OH)D compared with women regaining weight [14 nmol/L (95% CI 6-22); P = .001].
    1 context sentence
    Summary · context
    Secondary analysis from a randomized placebo-controlled trial, designed to investigate the efficacy of 52 weeks of treatment with either liraglutide, exercise, or both combined compared with placebo on weight loss maintenance after an 8-week low-calorie diet-induced weight loss in 195 individuals wi…

    In this study, Liraglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Liraglutide.

  2. 02HumanNot a test of Liraglutide aloneObservational studyOther

    In women with obesity in the pooled liraglutide/exercise/placebo trial, those losing further weight had lower baseline 25(OH)D than regainers (54 [SD 19] versus 70 [SD 25] nmol/L; P < .001).

    In plain wordsIn women with obesity in the mixed-intervention trial including liraglutide, further weight losers had lower starting vitamin D than regainers.

    Outcome
    DecreaseBaseline serum 25-hydroxyvitamin D by later weight-loss status
    Study

    n: not reported in source

    Comparator
    Women regaining weight
    Outcome group
    Metabolic pathways and metabolomics · Endocrine and hormones

    Measurements

    Baseline 25-hydroxyvitamin D
    54 nmol/L
    further-weight-loss group; SD 19; P < .001 versus regainers
    Baseline 25-hydroxyvitamin D
    70 nmol/L
    weight-regain group; SD 25

    Source sentences

    Summary
    Interestingly, women experiencing further weight loss at week 52 had a lower serum 25(OH)D at baseline compared with women regaining weight [54 nmol/L (SD 19) vs 70 nmol/L (SD 25), P < .001.].
    1 context sentence
    Summary · context
    Secondary analysis from a randomized placebo-controlled trial, designed to investigate the efficacy of 52 weeks of treatment with either liraglutide, exercise, or both combined compared with placebo on weight loss maintenance after an 8-week low-calorie diet-induced weight loss in 195 individuals wi…

    In this study, Liraglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Liraglutide.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Registered trials1

Trials this study reports on, or that list this study as a reference. Registry data from ClinicalTrials.gov.

1 trial · source ClinicalTrials.gov (opens in a new tab)

Status unknownPhase 4NCT04122716

Combined Effects of GLP-1 Analogue and Exercise on Maintenance of Weight Loss and Health After Very-low Calorie Diet

Signe Torekovn = 215Sept 2016 to est. Nov 2021

Obesity

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 11:11 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:05 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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