A mechanistic model of drug release from PLGA-based solid implants was validated with in vitro release data from implants of four drugs, including afamelanotide.
In plain wordsA computer model of drug release from PLGA implants was checked against lab release data for four drugs, one of which is afamelanotide.
- Peptide
- Melanotan I (afamelanotide)
- Outcome
- Not applicableValidation of PLGA implant release model with in vitro release data
- Study
n: not reported in source
Mechanistic model of PLGA solid implants- Outcome group
- Formulation, delivery and stability · Pharmacology
Source sentences
The model has been validated using in vitro release data obtained from implants of four drugs (buserelin, afamelanotide, brimonidine, and nafarelin).
1 context sentence(design, population, supporting numbers)
In the current study, we developed a mechanistic model for the in vitro drug release of PLGA-based solid implants.
In this study, Melanotan I (afamelanotide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan I (afamelanotide).