Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study.

Lee E, Walker C, Ayadi B

Alternative therapies in health and medicine1 Oct 2024Cited by 8 (Europe PMC)

PMID39325560PepBankPUB-39325560

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

01HumanNon-randomized trialEfficacy outcome
In women with interstitial cystitis who did not respond to pentosan polysulfate, 10 of 12 reported complete resolution of symptoms after one BPC‑157 treatment.
In plain wordsIn 12 women with a painful bladder condition, 10 reported all symptoms gone after one BPC‑157 treatment. There was no control group.
Peptide
BPC-157
Outcome
IncreaseComplete resolution of symptoms after one treatment
Study
n = 12
Outcome group
Urinary continence and bladder function · Kidney and urinary
Studied dose
10 mg total · injection around the inflamed bladder area during cystoscopy · single procedureAs given in this study (human).
Measurements
Patients with complete symptom resolution
10 of 12 patients
BPC-157, 100% success rating
Source sentences
Summary
Complete resolution of symptoms after one treatment was reported in 10 of 12 patients, who rated their success at 100%.
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve women between the ages of 39 and 76 years with a mean age of 58.3 years participated in this trial at a private clinic.
Summary · context
The women underwent cystoscopy and were treated with injections of the peptide BPC-157 (total of 10 mg) around the area of inflammation of the bladder during a single procedure.
Report a problemFND-3932556001
02HumanNon-randomized trialEfficacy outcome
In women with interstitial cystitis who did not respond to pentosan polysulfate, 2 of 12 rated their success at 80% after BPC‑157, with about 20% of symptoms lingering.
In plain wordsIn 12 women with a painful bladder condition, 2 said most symptoms went away after BPC‑157, but about 20% stayed. There was no control group.
Peptide
BPC-157
Outcome
IncreasePartial symptom resolution
Study
n = 12
Outcome group
Urinary continence and bladder function · Kidney and urinary
Studied dose
10 mg total · injection around the inflamed bladder area during cystoscopy · single procedureAs given in this study (human).
Measurements
Patients rating success at 80%
2 of 12 patients
BPC-157
Source sentences
Summary
The remaining 2 of 12 patients rated their success at 80%, with most symptoms resolved but about 20% of their symptoms lingering.
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve women between the ages of 39 and 76 years with a mean age of 58.3 years participated in this trial at a private clinic.
Summary · context
The women underwent cystoscopy and were treated with injections of the peptide BPC-157 (total of 10 mg) around the area of inflammation of the bladder during a single procedure.
Report a problemFND-3932556002
03HumanNon-randomized trialEfficacy outcome
In women with interstitial cystitis who did not respond to pentosan polysulfate, all 12 scored 5/5 on the Global Response Assessment after BPC‑157.
In plain wordsIn 12 women with a painful bladder condition, all 12 gave the top score on a response questionnaire after BPC‑157. There was no control group.
Peptide
BPC-157
Outcome
IncreaseGlobal Response Assessment score
Study
n = 12
Outcome group
Urinary continence and bladder function · Kidney and urinary
Studied dose
10 mg total · injection around the inflamed bladder area during cystoscopy · single procedureAs given in this study (human).
Measurements
Global Response Assessment score
5 out of 5
all 12 patients
Source sentences
Summary
This therapy was successful because all 12 patients scored a 5/5 on the Global Response Assessment.
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve women between the ages of 39 and 76 years with a mean age of 58.3 years participated in this trial at a private clinic.
Summary · context
The women underwent cystoscopy and were treated with injections of the peptide BPC-157 (total of 10 mg) around the area of inflammation of the bladder during a single procedure.
Report a problemFND-3932556003
04HumanNon-randomized trialSafety outcome
In women with interstitial cystitis treated with BPC‑157, no one dropped out of the study.
In plain wordsIn 12 women given BPC‑157 for a painful bladder condition, no one left the study.
Peptide
BPC-157
Outcome
No significant changeStudy dropout
Study
n = 12
Outcome group
Adverse events · Kidney and urinary
Studied dose
10 mg total · injection around the inflamed bladder area during cystoscopy · single procedureAs given in this study (human).
Source sentences
Summary
No one dropped out of the study, and no adverse events were reported.
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve women between the ages of 39 and 76 years with a mean age of 58.3 years participated in this trial at a private clinic.
Summary · context
The women underwent cystoscopy and were treated with injections of the peptide BPC-157 (total of 10 mg) around the area of inflammation of the bladder during a single procedure.
Report a problemFND-3932556004
05HumanNon-randomized trialSafety outcome
In women with interstitial cystitis treated with BPC‑157, no adverse events were reported.
In plain wordsIn 12 women given BPC‑157 for a painful bladder condition, no side effects were reported. The group was small.
Peptide
BPC-157
Outcome
No significant changeAdverse events
Study
n = 12
Outcome group
Adverse events · Kidney and urinary
Studied dose
10 mg total · injection around the inflamed bladder area during cystoscopy · single procedureAs given in this study (human).
Source sentences
Summary
no adverse events were reported.
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve women between the ages of 39 and 76 years with a mean age of 58.3 years participated in this trial at a private clinic.
Summary · context
The women underwent cystoscopy and were treated with injections of the peptide BPC-157 (total of 10 mg) around the area of inflammation of the bladder during a single procedure.
Report a problemFND-3932556005

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 3Current
10 Oct 2026, 08:19 UTC
Study results updated
Version 2
9 Oct 2026, 03:03 UTC
Study data updated · source update from Europe PMC
Version 1
9 Oct 2026, 02:56 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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