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Study · Case report or series · n = 1 · 2024

3 results

Semaglutide Treatment in a Patient with Extreme Obesity and Massive Lymphedema: A Case Report.

Nguyen JT, Barbet-Massin MA, Pupier E, Larroumet A, Bosc L, Michelet M, Monsaingeon-Henry M, Gatta-Cherifi B

Obesity facts9 Sept 2024Cited by 4 (Europe PMC)

PMID39250902 (opens in a new tab)PMCIDPMC11661835 (opens in a new tab)DOI10.1159/000540241 (opens in a new tab)PepBankPUB-39250902
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanCase report or seriesEfficacy outcome

    In a man with extreme obesity and massive lymphedema, semaglutide with multidisciplinary care was followed by a 40 kg (15.7%) loss of body weight at 28 weeks.

    In plain wordsIn one man with extreme obesity, weight fell by 40 kg after 28 weeks of semaglutide with team care.

    Peptide
    Semaglutide
    Outcome
    DecreaseWeight loss at 28 weeks
    Study

    n = 1

    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    maximal 1 mg/week, decreased to 0.25 mg/week · 28 weeksAs given in this study (human).

    Measurements

    Weight loss
    40 kg
    28 weeks
    Total body weight loss
    15.7%
    28 weeks

    Source sentences

    Summary
    At 28 weeks of therapy, the patient had lost 40 kg or 15.7% of his total body weight.
    3 context sentences
    Summary · context
    We present a 43-year-old male who was admitted to our specialized obesity center for weight management.
    Summary · context
    His initial weight was 255 kg and BMI was 93.7 kg/m2.
    Summary · context
    Treatment with semaglutide was started in hospital and continued at home.
  2. 02HumanCase report or seriesEfficacy outcome

    In a man with extreme obesity and massive lymphedema, lymphedema decreased on semaglutide, with at least 16 cm lost from the left thigh circumference.

    In plain wordsIn one man with extreme obesity, leg swelling decreased on semaglutide and the left thigh became at least 16 cm smaller.

    Peptide
    Semaglutide
    Outcome
    DecreaseMassive localized lymphedema (thigh circumference)
    Study

    n = 1

    Outcome group
    Vascular function · Cardiovascular
    Studied dose
    maximal 1 mg/week, decreased to 0.25 mg/week · 28 weeksAs given in this study (human).

    Measurements

    Thigh circumference loss
    ≥ 16 cm
    left thigh

    Source sentences

    Summary
    His lymphedema decreased; he had lost at least 16 cm of his left thigh circumference.
    3 context sentences
    Summary · context
    We present a 43-year-old male who was admitted to our specialized obesity center for weight management.
    Summary · context
    His initial weight was 255 kg and BMI was 93.7 kg/m2.
    Summary · context
    Treatment with semaglutide was started in hospital and continued at home.
  3. 03HumanCase report or seriesEfficacy outcome

    In a bedridden man with extreme obesity, the patient was able to walk again and regain autonomy in daily activities after semaglutide treatment with team care.

    In plain wordsOne man with extreme obesity could walk again and manage daily activities after semaglutide treatment with team care.

    Peptide
    Semaglutide
    Outcome
    IncreaseMobility and daily activities
    Study

    n = 1

    Outcome group
    Exercise and physical function · Whole body
    Studied dose
    maximal 1 mg/week, decreased to 0.25 mg/week · 28 weeksAs given in this study (human).

    Source sentences

    Summary
    He was able to walk again and regain autonomy of his daily activities of living.
    3 context sentences
    Summary · context
    We present a 43-year-old male who was admitted to our specialized obesity center for weight management.
    Summary · context
    His initial weight was 255 kg and BMI was 93.7 kg/m2.
    Summary · context
    Treatment with semaglutide was started in hospital and continued at home.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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