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Study · Not a test of the peptide alone · 2024

1 result

Structural basis for the ligand recognition and G protein subtype selectivity of kisspeptin receptor.

Wu Z, Chen G, Qiu C, Yan X, Xu L, Jiang S, Xu J, Han R, Shi T, Liu Y, Gao W, Wang Q and 8 more

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Li J, Ye F, Pan X, Zhang Z, Ning P, Zhang B, Chen J, Du Y

Science advances16 Aug 2024Cited by 16 (Europe PMC)

PMID39151001 (opens in a new tab)PMCIDPMC11328905 (opens in a new tab)DOI10.1126/sciadv.adn7771 (opens in a new tab)PepBankPUB-39151001
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-54 (metastin).

  1. 01LabNot a test of Kisspeptin-54 (metastin) aloneIn vitro (cell-free)Mechanism

    In cell-free structural work, the cryo-EM structure of the KISS1R-Gq complex bound to the endogenous agonist KP54 was resolved.

    In plain wordsIn lab tests, researchers solved the structure of the kisspeptin receptor with kisspeptin‑54 attached.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    Not applicableCryo-EM structure of KISS1R-Gq bound to KP54
    Study

    n: not reported in source

    cryo-EM structures of the KISS1R-Gq complex
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    structure of KISS1R-Gq complex bound to the endogenous agonist KP54.

    In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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