In Veterans with obesity, semaglutide produced less weight loss at 0-3 months than intragastric balloon (-5.1 kg versus -11.8 kg).
In plain wordsIn Veterans with obesity, semaglutide gave less weight loss in the first 3 months than the intragastric balloon.
- Peptide
- Semaglutide
- Outcome
- IncreaseWeight change 0-3 months
- Study
n = 113
- Comparator
- Intragastric balloon
- Outcome group
- Body weight · Metabolic and weight
- Studied dose
- Dose not stated
Measurements
- Weight change 0-3 months
- −5.1 kg
- semaglutide
- Weight change 0-3 months
- −11.8 kg
- intragastric balloon
Source sentences
Weight (kg) change was measured at intervals: 0-3 months:- 11.8(- 17,- 9.5) IGB vs. - 5.1(- 7.4,- 2.3) semaglutide, p < 0.0001; 0-6 months:- 12.7(- 18.4,- 9.9) vs. - 9.4(- 12.6,- 6.1), p = 0.03; 3-6 months:- 0.5(- 2.3,2.3) vs. - 4.3(- 6.8,- 1.6), p < 0.0001; 6-12 months:3(0,7.3) vs. - 1.9(- 4.7,1), p = 0.0006.
2 context sentences(design, population, supporting numbers)
Retrospective review of prospective databases of perioperatively placed intragastric balloon cohort from 1/2019-1/2023 compared to patients who received initiatory GLP1RA from 6/2021-8/2022 at a VA Medical Center(VAMC).
Seventeen (15%) patients underwent IGB placement and 96 (85%) patients received semaglutide.