In patients undergoing cardiac surgery, preoperative liraglutide increased perioperative glycemic time in range (72% versus 47%) compared with placebo.
In plain wordsIn patients having heart surgery, liraglutide before surgery kept blood sugar in range for more of the time than placebo.
- Peptide
- Liraglutide
- Outcome
- IncreaseGlycemic time in range by CGM
- Study
n = 25
- Comparator
- Placebo
- Outcome group
- Glycemic control · Metabolic and weight
- Studied dose
- Dose not stated
Measurements
- Time in range
- 72%
- liraglutide
- Time in range
- 47%
- control
- Absolute difference
- 25%
- liraglutide vs control
Source sentences
Liraglutide increased glycemic time in range 72% versus 47% in the control group (absolute difference 25%, 95% confidence interval -41.4 to -8.9, p = .004).
2 context sentences(design, population, supporting numbers)
This was a prospective, single-center, prespecified analysis of the GLOBE trial, a randomized controlled trial comparing preoperative liraglutide treatment to placebo in patients undergoing cardiac surgery.
Twenty-five patients undergoing cardiac surgery were recruited from the hospital's cardiac surgery department.