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Study · Animal study (in vivo) · catfish (clarias batrachus) · 2024

7 results

Nitric oxide mediated kisspeptin regulation of steroidogenesis and gametogenesis in the catfish, Clarias batrachus.

Singh A, Lal B, Kumar P, Parhar IS, Millar RP

Cell and tissue research3 Jun 2024Cited by 1 (Europe PMC)

PMID38829397 (opens in a new tab)DOI10.1007/s00441-024-03899-2 (opens in a new tab)PepBankPUB-38829397
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In catfish, KP-10 increased gonadal expression of all nitric oxide synthase isoforms (iNOS, eNOS, nNOS).

    In plain wordsIn catfish, KP-10 raised the expression of all three nitric oxide synthase enzymes in the gonads.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseNOS isoform expression in gonads (in vivo)
    Study

    catfish (Clarias batrachus)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, KP-10 increased the expression of all the isoforms of NOSs (iNOS, eNOS, nNOS) and concurrently NO and steroids in the ovary and testis.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In catfish, KP-10 increased nitric oxide in the ovary and testis.

    In plain wordsIn catfish, KP-10 raised nitric oxide in the ovary and testis.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseNitric oxide production in ovary and testis (in vivo)
    Study

    catfish (Clarias batrachus)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, KP-10 increased the expression of all the isoforms of NOSs (iNOS, eNOS, nNOS) and concurrently NO and steroids in the ovary and testis.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In catfish, KP-10 increased steroid production in the ovary and testis.

    In plain wordsIn catfish, KP-10 raised steroid hormone production in the ovary and testis.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseSteroid production in ovary and testis (in vivo)
    Study

    catfish (Clarias batrachus)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, KP-10 increased the expression of all the isoforms of NOSs (iNOS, eNOS, nNOS) and concurrently NO and steroids in the ovary and testis.
  4. 04LabEx vivo tissueMechanism

    In catfish gonadal explants, kisspeptin stimulated nitric oxide production.

    In plain wordsIn lab-cultured catfish gonad tissue, kisspeptin raised nitric oxide production.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseNitric oxide production in gonadal explants and medium
    Study

    catfish (Clarias batrachus)n: not reported in source

    Catfish gonadal explants
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In vitro studies also indicate that kisspeptin stimulates the production of NO and estradiol and testosterone levels in the gonadal explants and medium.
  5. 05LabEx vivo tissueEfficacy outcome

    In catfish gonadal explants, kisspeptin increased estradiol levels.

    In plain wordsIn lab-cultured catfish gonad tissue, kisspeptin raised estradiol levels.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseEstradiol level in gonadal explants and medium
    Study

    catfish (Clarias batrachus)n: not reported in source

    Catfish gonadal explants
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In vitro studies also indicate that kisspeptin stimulates the production of NO and estradiol and testosterone levels in the gonadal explants and medium.
  6. 06LabEx vivo tissueEfficacy outcome

    In catfish gonadal explants, kisspeptin increased testosterone levels.

    In plain wordsIn lab-cultured catfish gonad tissue, kisspeptin raised testosterone levels.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseTestosterone level in gonadal explants and medium
    Study

    catfish (Clarias batrachus)n: not reported in source

    Catfish gonadal explants
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In vitro studies also indicate that kisspeptin stimulates the production of NO and estradiol and testosterone levels in the gonadal explants and medium.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 07AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In catfish, the nitric oxide synthase inhibitor L-NAME suppressed expression of kiss1 in the gonads.

    In plain wordsIn catfish, a nitric oxide blocker lowered the gonads' own kisspeptin gene expression.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseGonadal kiss1 expression after L-NAME
    Study

    catfish (Clarias batrachus)n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    The results revealed that L-NAME suppressed the expression of kiss1 in gonads of the catfish establishing the role of NO in kisspeptin expression.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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