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Study · Not a test of the peptide alone · 2022

5 results

Probing for peptidic drugs (2-10 kDa) in doping control blood samples.

Thomas A, Thilmany S, Hofmann A, Thevis M

Analytical science advances22 Aug 2022Cited by 7 (Europe PMC)

PMID38716080 (opens in a new tab)PMCIDPMC10989627 (opens in a new tab)DOI10.1002/ansa.202200027 (opens in a new tab)PepBankPUB-38716080
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, the peptide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking the peptide.

  1. 01LabNot a test of CJC-1295 (with DAC) aloneOther designOther

    Generic mixed-mode solid-phase extraction with high-resolution mass spectrometry co-extracted and analysed CJC‑1295 in blood with criteria that fulfil the WADA TD2022 MRPL requirements.

    In plain wordsIn lab tests, one blood method could detect CJC‑1295 along with other banned peptides and meet anti-doping requirements.

    Peptide
    CJC-1295 (with DAC)
    Outcome
    Not applicableCo-extraction and detection in blood meeting WADA MRPL
    Study

    n: not reported in source

    Doping control blood samples
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    growth hormone releasing hormones (sermorelin, CJC-1295 and tesamorelin), insulin-like growth factors (long-R3-IGF-I, R3-IGF-I and Des1-3-IGF-I) and mechano growth factors (human MGF and MGF-Goldspink) with criteria that fulfil the requirements of the WADA documents (TD2022 MRPL)

    In this study, CJC-1295 (with DAC) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking CJC-1295 (with DAC).

  2. 02LabNot a test of Tesamorelin aloneOther designOther

    Generic mixed-mode solid-phase extraction with high-resolution mass spectrometry co-extracted and analysed tesamorelin in blood with criteria that fulfil the WADA TD2022 MRPL requirements.

    In plain wordsIn lab tests, one blood method could detect tesamorelin along with other banned peptides and meet anti-doping requirements.

    Peptide
    Tesamorelin
    Outcome
    Not applicableCo-extraction and detection in blood meeting WADA MRPL
    Study

    n: not reported in source

    Doping control blood samples
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    growth hormone releasing hormones (sermorelin, CJC-1295 and tesamorelin), insulin-like growth factors (long-R3-IGF-I, R3-IGF-I and Des1-3-IGF-I) and mechano growth factors (human MGF and MGF-Goldspink) with criteria that fulfil the requirements of the WADA documents (TD2022 MRPL)

    In this study, Tesamorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Tesamorelin.

  3. 03LabNot a test of Sermorelin aloneOther designOther

    A generic mixed-mode solid-phase extraction with LC-HRMS allowed co-extraction and analysis of several peptides in blood, including sermorelin, with criteria that fulfil WADA requirements.

    In plain wordsA lab method could extract and detect sermorelin and other banned peptides in blood samples together.

    Peptide
    Sermorelin
    Outcome
    Not applicableCo-extraction and detection in blood samples
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    This facilitates the analysis, and a generic sample preparation by means of mixed-mode solid-phase extraction could be realized in this study.
    2 context sentences
    Summary · context
    growth hormone releasing hormones (sermorelin, CJC-1295 and tesamorelin), insulin-like growth factors (long-R3-IGF-I, R3-IGF-I and Des1-3-IGF-I) and mechano growth factors (human MGF and MGF-Goldspink) with criteria that fulfil the requirements of the WADA documents…
    Summary · context
    In contrast to urine, blood analysis essentially relies on the detection of intact peptide hormones, and the expected concentrations are commonly higher in blood samples than in urine.

    In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Sermorelin.

  4. 04LabNot a test of MGF / PEG-MGF aloneOther designOther

    A generic sample preparation by mixed-mode solid-phase extraction could be realized for peptide drugs in blood samples, including MGF forms.

    In plain wordsIn lab tests, one simple sample preparation worked for many peptide drugs in blood, including MGF forms.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableGeneric sample preparation for peptides in blood
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    This facilitates the analysis, and a generic sample preparation by means of mixed-mode solid-phase extraction could be realized in this study.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  5. 05LabNot a test of MGF / PEG-MGF aloneOther designOther

    Co-extraction and analysis of several peptides, including human MGF and MGF-Goldspink, fulfilled the WADA TD2022 MRPL requirements.

    In plain wordsIn lab tests, the method detected several peptide drugs, including MGF forms, at the performance level anti-doping rules require.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableCo-extraction of peptides including MGF to WADA criteria
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    mechano growth factors (human MGF and MGF-Goldspink) with criteria that fulfil the requirements of the WADA documents (TD2022 MRPL) for doping controls.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 25 to 48Current

    28 Oct 2026, 02:04 UTC

    The same notice was added 24 times, first on 13 Oct 2026, 21:43 UTC. The status did not change between them.

    Study results updated

  2. Version 24

    13 Oct 2026, 16:31 UTC

    Study data updated · source update from Europe PMC

  3. Versions 4 to 23

    13 Oct 2026, 14:22 UTC

    The same notice was added 20 times, first on 9 Oct 2026, 18:17 UTC. The status did not change between them.

    Study results updated

  4. Versions 2 to 3

    9 Oct 2026, 03:13 UTC

    The same notice was added 2 times, first on 9 Oct 2026, 03:13 UTC. The status did not change between them.

    Study data updated · source update from Europe PMC

  5. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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