In adults with type 2 diabetes, a network meta-analysis found that tirzepatide did not reduce all-cause mortality compared with usual care.
In plain wordsIn adults with type 2 diabetes, tirzepatide did not lower the risk of death from any cause compared with usual care.
- Peptide
- Tirzepatide
- Outcome
- No significant changeAll-cause mortality versus usual care
- Study
n: not reported in source
- Comparator
- Usual care
- Outcome group
- Mortality · Cardiovascular
- Studied dose
- Dose not stated
Source sentences
Compared with usual care, insulin, tirzepatide, and DPP4 inhibitors do not reduce all-cause mortality (low to high CoE).
1 context sentence(design, population, supporting numbers)
RCTs lasting at least 52 weeks that included at least 500 adults with T2DM receiving eligible medications and reported any outcomes of interest.