Skip to content

Study · Animal study (in vivo) · sterlet sturgeon (acipenser ruthenus) · 2024

11 results

Intraperitoneal administration of kisspeptin-10 modulates follicle maturation, gonadal steroids, calcium and metabolites in Sterlet sturgeon, Acipenser ruthenus.

Roosta Z, Unniappan S, Uju C, Rahmati M, Falahatkar B

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology23 Feb 2024Cited by 4 (Europe PMC)

PMID38401763 (opens in a new tab)DOI10.1016/j.cbpa.2024.111609 (opens in a new tab)PepBankPUB-38401763
Publisher pagePubMedAsk about this study
Jump to 11 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study11

11 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, KP-10 had no effect on body weight after 4 weeks of treatment.

    In plain wordsIn Sterlet sturgeon, KP-10 did not change body weight after 4 weeks.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeBody weight after 4 weeks
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    Dose not stated · intraperitoneal injection or slow release · 4 weeksAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    No effect for KP-10 on sturgeon body weight was found after 4 weeks of treatment.
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, plasma estradiol levels differed significantly between groups over time.

    In plain wordsIn Sterlet sturgeon, blood estradiol levels differed between treatment groups over time.

    Peptide
    Kisspeptin-10
    Outcome
    Direction not reportedPlasma 17β-estradiol
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    Multivariate analysis revealed a significant disparity in plasma E2 levels.
    2 context sentences
    Summary · context
    It was significantly different between groups (time, P = 0.0022).
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, estradiol in epithelial mucus differed significantly between and within groups in the acute group.

    In plain wordsIn Sterlet sturgeon, estradiol in skin mucus differed between and within groups in the acute group.

    Peptide
    Kisspeptin-10
    Outcome
    Direction not reported17β-estradiol in epithelial mucus (acute group)
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    E2 in epithelia mucosa showed significant difference between and within groups in the acute group (time, P = 0.0252; treatment, P = 0.0423; time × treatment, P = 0.0429).
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, testosterone levels were unaffected by the treatments.

    In plain wordsIn Sterlet sturgeon, testosterone levels did not change with the treatments.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeTestosterone levels
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    T levels were unaffected by treatments (P > 0.05).
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, synthetic acipenser KP-10 increased oocyte vitellogenin levels.

    In plain wordsIn Sterlet sturgeon, KP-10 raised vitellogenin, an egg yolk protein, in eggs.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseOocyte vitellogenin
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    The presence of synthetic aKP-10 led to an elevation in oocyte and plasma VTG levels (P < 0.05).
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, synthetic acipenser KP-10 increased plasma vitellogenin levels.

    In plain wordsIn Sterlet sturgeon, KP-10 raised vitellogenin, an egg yolk protein, in the blood.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePlasma vitellogenin
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    The presence of synthetic aKP-10 led to an elevation in oocyte and plasma VTG levels (P < 0.05).
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, prolonged exposure to KP-10 increased plasma calcium levels.

    In plain wordsIn Sterlet sturgeon, long exposure to KP-10 raised blood calcium.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePlasma calcium after prolonged exposure
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    Prolonged exposure to this peptide resulted in an increase in plasma calcium levels.
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  8. 08AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, KP-10 treatment was accompanied by an increase in the number of mature follicles.

    In plain wordsIn Sterlet sturgeon, KP-10 treatment came with more mature egg follicles.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseNumber of mature follicles
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    Simultaneously, there was an augmentation in the number of mature follicles.
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  9. 09AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, acipenser KP-10 significantly elevated plasma glucose regardless of exposure duration.

    In plain wordsIn Sterlet sturgeon, KP-10 raised blood glucose.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePlasma glucose
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    Regardless of the duration of exposure, aKP-10 significantly elevated plasma glucose levels in Sterlet (P < 0.0).
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  10. 10AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, KP-10 increased plasma lipids.

    In plain wordsIn Sterlet sturgeon, KP-10 raised blood fats.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePlasma lipids
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    Additionally, KP-10 led to an increase in plasma lipids and cholesterol in Sterlet.
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.
  11. 11AnimalAnimal study (in vivo)Efficacy outcome

    In Sterlet sturgeon, KP-10 increased plasma cholesterol.

    In plain wordsIn Sterlet sturgeon, KP-10 raised blood cholesterol.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePlasma cholesterol
    Study

    Sterlet sturgeon (Acipenser ruthenus)n: not reported in source

    Comparator
    Saline injection and no-treatment controls
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    Dose not stated · intraperitoneal injection or slow releaseAs given in this study (Sterlet sturgeon (Acipenser ruthenus)).

    Source sentences

    Summary
    Additionally, KP-10 led to an increase in plasma lipids and cholesterol in Sterlet.
    1 context sentence
    Summary · context
    Mature Sterlet sturgeon were grouped into six groups: saline i.p injection (control), human kisspeptin (hKP-10) i.p injection; acipenser kisspeptin (aKP-10) i.p injection; hKP-10 (slow release); aKP-10 (slow-release) and no treatment control.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.