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Study · Case report or series · n = 4 · 2024

2 results

Hot Water Eliminates the Bitter Taste of Oral Semaglutide: A Report of Four Cases.

Okada S, Okada J, Okada K, Yamada E, Saito T, Kikkawa K, Ando T, Ohshima K

Internal medicine (Tokyo, Japan)13 Jan 2024Cited by 2 (Europe PMC)

PMID38220187 (opens in a new tab)PMCIDPMC11414362 (opens in a new tab)DOI10.2169/internalmedicine.2608-23 (opens in a new tab)PepBankPUB-38220187
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanCase report or seriesOther

    In four patients with type 2 diabetes, taking oral semaglutide with hot water above 46.0°C but below 52.0°C removed the perceived bitter taste.

    In plain wordsIn four people with type 2 diabetes, taking oral semaglutide with hot water at about 46 to 52°C removed the bitter taste.

    Peptide
    Semaglutide
    Outcome
    DecreaseBitter taste perception with hot water
    Study

    n = 4

    Outcome group
    Adverse events · Gastrointestinal
    Studied dose
    Dose not stated · oralAs given in this study (human).

    Source sentences

    Summary
    When the hot water temperature was increased to above 46.0°C but below 52.0°C, no bitter taste was perceived, with the daily mean interstitial glucose level remaining at the target range.
    2 context sentences
    Title · context
    Hot Water Eliminates the Bitter Taste of Oral Semaglutide: A Report of Four Cases.
    Summary · context
    Semaglutide is a well-designed drug with a special coating that allows for oral administration to patients with type 2 diabetes mellitus.
  2. 02HumanCase report or seriesEfficacy outcome

    In four patients with type 2 diabetes taking oral semaglutide with hot water, daily mean interstitial glucose stayed in the target range.

    In plain wordsIn four people with type 2 diabetes, blood sugar stayed in the target range when oral semaglutide was taken with hot water.

    Peptide
    Semaglutide
    Outcome
    No significant changeDaily mean interstitial glucose with hot water dosing
    Study

    n = 4

    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated · oralAs given in this study (human).

    Source sentences

    Summary
    When the hot water temperature was increased to above 46.0°C but below 52.0°C, no bitter taste was perceived, with the daily mean interstitial glucose level remaining at the target range.
    2 context sentences
    Title · context
    Hot Water Eliminates the Bitter Taste of Oral Semaglutide: A Report of Four Cases.
    Summary · context
    Semaglutide is a well-designed drug with a special coating that allows for oral administration to patients with type 2 diabetes mellitus.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:04 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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