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Study · Case report or series · n = 6 · 2023

2 results

Significant Decrease in Alcohol Use Disorder Symptoms Secondary to Semaglutide Therapy for Weight Loss: A Case Series.

Richards JR, Dorand MF, Royal K, Mnajjed L, Paszkowiak M, Simmons WK

The Journal of clinical psychiatry27 Nov 2023Cited by 51 (Europe PMC)

PMID38019594 (opens in a new tab)DOI10.4088/jcp.23m15068 (opens in a new tab)PepBankPUB-38019594
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanCase report or seriesEfficacy outcome

    In 6 patients with alcohol use disorder treated with semaglutide for weight loss, the mean AUDIT score fell by 9.5 points.

    In plain wordsIn six people with alcohol use disorder given semaglutide for weight loss, alcohol-use scores fell by about 9.5 points on average.

    Peptide
    Semaglutide
    Outcome
    DecreaseAUDIT score decrease
    Study

    n = 6

    Outcome group
    Addiction, withdrawal and alcohol intake · Mental health and mood
    Studied dose
    Dose not stated

    Measurements

    AUDIT score mean decrease
    9.5 points
    6 patients

    Source sentences

    Summary
    All 6 identified patients (100%) had significant reduction in AUD symptomatology based on AUDIT score improvement following treatment with semaglutide (mean decrease of 9.5 points, P < .001).
    1 context sentence
    Summary · context
    This case series presents 6 patients with positive AUD screenings who were treated with semaglutide for weight loss.
  2. 02HumanCase report or seriesEfficacy outcome

    In 6 patients with alcohol use disorder treated with semaglutide for weight loss, all 6 (100%) had a significant reduction in AUD symptoms.

    In plain wordsIn six people with alcohol use disorder given semaglutide for weight loss, all six had fewer alcohol-use symptoms afterward.

    Peptide
    Semaglutide
    Outcome
    DecreasePatients with reduced AUD symptoms
    Study

    n = 6

    Outcome group
    Addiction, withdrawal and alcohol intake · Mental health and mood
    Studied dose
    Dose not stated

    Measurements

    Patients with AUDIT reduction
    100%
    6 of 6 patients

    Source sentences

    Summary
    All 6 identified patients (100%) had significant reduction in AUD symptomatology based on AUDIT score improvement following treatment with semaglutide
    1 context sentence
    Summary · context
    This case series presents 6 patients with positive AUD screenings who were treated with semaglutide for weight loss.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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