The Platelet membranes-ICG-SS31-PLGA nano-system accumulated within the kidney as acute kidney injury progressed.
In plain wordsA nanoparticle carrying SS31 and a dye built up in the kidney as kidney injury worsened.
- Peptide
- Elamipretide (SS-31)
- Outcome
- IncreaseKidney accumulation of PISP nano-system
- Study
n: not reported in source
Kidney injury (not stated)- Outcome group
- Pharmacokinetics · Kidney and urinary
Source sentences
This approach allowed for the accumulation of PISP within the kidney as the disease progresses.
1 context sentence(design, population, supporting numbers)
In this study, we aimed to address these challenges by developing a nano-system called Platelet membranes-ICG-SS31-PLGA (PISP), which was designed to selectively target to the kidney site, taking advantage of the natural tendency of platelets to accumulate at sites of vascular injury.
In this study, Elamipretide (SS-31) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Elamipretide (SS-31).