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Study · Measured the body's own peptide · 2023

5 results

Age-related Changes in Humanin Expression in the Ovarian Tissue of Rat.

Xia Y, Zhang HY, Ma S, Zhou F

Current medical science28 Apr 2023Cited by 3 (Europe PMC)

PMID37115400 (opens in a new tab)DOI10.1007/s11596-023-2732-7 (opens in a new tab)PepBankPUB-37115400
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, natural humanin was expressed in the cytoplasm of oocytes, interstitial, granulosa and theca cells and in the corpus luteum.

    In plain wordsIn rats, the body's own humanin was found in several cell types of the ovary.

    Peptide
    Humanin
    Outcome
    Not applicableHumanin localization in ovarian tissue
    Study

    ratn = 40

    Ovarian tissue of Sprague-Dawley rats by age
    Outcome group
    Aging markers · Reproductive and sexual health

    Source sentences

    Summary
    The immunofluorescence and immunohistochemical results confirmed that humanin was expressed in rat ovarian tissues. In addition, cellular localization analysis showed that humanin was expressed in the cytoplasm of oocytes, interstitial cells, granulosa cells and theca cells in all levels of follicle…
    1 context sentence
    Summary · context
    A total of 40 Sprague-Dawley rats of various ages (2, 12, 30, and 60 days old and 1 year old) were grouped by age.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    Ovarian humanin mRNA in 12-day-old rats was not significantly higher than in 2-day-old rats.

    In plain wordsIn rats, the body's own ovarian humanin was not clearly different at 12 days than at 2 days of age.

    Peptide
    Humanin
    Outcome
    No significant changeHumanin mRNA in 12-day-old versus 2-day-old rats
    Study

    ratn: not reported in source

    Ovarian tissue of Sprague-Dawley rats by age
    Comparator
    2-day-old rats
    Outcome group
    Aging markers · Reproductive and sexual health

    Source sentences

    Summary
    level of humanin expression in the ovarian tissues of 12-day-old rats was non-significantly higher than that in the ovarian tissues of 2-day-old rats (P>0.05)
    1 context sentence
    Summary · context
    A total of 40 Sprague-Dawley rats of various ages (2, 12, 30, and 60 days old and 1 year old) were grouped by age.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    Ovarian humanin mRNA in 30-day-old, 60-day-old and 1-year-old rats was significantly lower than in 2-day-old rats.

    In plain wordsIn rats, the body's own ovarian humanin was lower at older ages than at 2 days of age.

    Peptide
    Humanin
    Outcome
    DecreaseHumanin mRNA in 30-day, 60-day and 1-year-old versus 2-day-old rats
    Study

    ratn: not reported in source

    Ovarian tissue of Sprague-Dawley rats by age
    Comparator
    2-day-old rats
    Outcome group
    Aging markers · Reproductive and sexual health

    Source sentences

    Summary
    whereas the levels of humanin expression in the ovarian tissues of 30-day-old, 60-day-old, and 1-year-old rats were significantly lower than that in the ovarian tissues of 2-day-old rats (P<0.05).
    1 context sentence
    Summary · context
    A total of 40 Sprague-Dawley rats of various ages (2, 12, 30, and 60 days old and 1 year old) were grouped by age.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    Ovarian humanin protein in 60-day-old and 1-year-old rats was significantly lower than in 2-day-old rats.

    In plain wordsIn rats, the body's own ovarian humanin protein was lower at older ages than at 2 days of age.

    Peptide
    Humanin
    Outcome
    DecreaseHumanin protein in 60-day and 1-year-old versus 2-day-old rats
    Study

    ratn: not reported in source

    Ovarian tissue of Sprague-Dawley rats by age
    Comparator
    2-day-old rats
    Outcome group
    Aging markers · Reproductive and sexual health

    Source sentences

    Summary
    The Western blotting results demonstrated that the levels of humanin protein expression in the ovarian tissues of 60-day-old and 1-year-old rats were significantly lower than those of 2-day-old rats (P<0.01)
    1 context sentence
    Summary · context
    A total of 40 Sprague-Dawley rats of various ages (2, 12, 30, and 60 days old and 1 year old) were grouped by age.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

  5. 05AnimalEndogenous levelAnimal study (in vivo)Other

    Ovarian humanin protein did not differ significantly between 12-day-old and 30-day-old rats.

    In plain wordsIn rats, the body's own ovarian humanin protein was not clearly different between 12 and 30 days of age.

    Peptide
    Humanin
    Outcome
    No significant changeHumanin protein in 12-day-old versus 30-day-old rats
    Study

    ratn: not reported in source

    Ovarian tissue of Sprague-Dawley rats by age
    Comparator
    30-day-old rats
    Outcome group
    Aging markers · Reproductive and sexual health

    Source sentences

    Summary
    whereas there was no significant difference in the level of humanin protein expression between the ovarian tissues of 12-day-old and 30-day-old rats.
    1 context sentence
    Summary · context
    A total of 40 Sprague-Dawley rats of various ages (2, 12, 30, and 60 days old and 1 year old) were grouped by age.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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