Skip to content

Study · Ex vivo tissue · cat · 2023

7 results

Role of kisspeptin-10 and betacellulin in control of feline ovarian cell functions.

Loncová B, Fabová Z, Sirotkin AV

Reproductive biology12 Apr 2023Cited by 8 (Europe PMC)

PMID37058773 (opens in a new tab)DOI10.1016/j.repbio.2023.100762 (opens in a new tab)PepBankPUB-37058773
Publisher pagePubMedAsk about this study
Jump to 7 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueEfficacy outcome

    In cultured feline ovarian cells, KISS alone increased proliferation.

    In plain wordsIn cat ovarian cells in lab culture, kisspeptin increased cell proliferation.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseCell proliferation (cyclin B1)
    Study

    catn: not reported in source

    cultured feline ovarian fragments and granulosa cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    10 ng/mlAs given in this study (cat).

    Source sentences

    Summary
    The addition of KISS alone increased proliferation, apoptosis, progesterone, estradiol release, and decreased testosterone but did not affect viability.
    1 context sentence
    Summary · context
    For this purpose, we examined (1) the effect of the addition of BTC (0, 1, 10, and 100 ng/ml) given alone or in combination with KISS (10 ng/ml) on cultured feline ovarian fragments or granulosa cells.
  2. 02LabEx vivo tissueEfficacy outcome

    In cultured feline ovarian cells, KISS alone increased apoptosis.

    In plain wordsIn cat ovarian cells in lab culture, kisspeptin increased cell death (apoptosis).

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseApoptosis (bax)
    Study

    catn: not reported in source

    cultured feline ovarian fragments and granulosa cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    10 ng/mlAs given in this study (cat).

    Source sentences

    Summary
    The addition of KISS alone increased proliferation, apoptosis, progesterone, estradiol release, and decreased testosterone but did not affect viability.
    1 context sentence
    Summary · context
    For this purpose, we examined (1) the effect of the addition of BTC (0, 1, 10, and 100 ng/ml) given alone or in combination with KISS (10 ng/ml) on cultured feline ovarian fragments or granulosa cells.
  3. 03LabEx vivo tissueEfficacy outcome

    In cultured feline ovarian cells, KISS alone increased progesterone release.

    In plain wordsIn cat ovarian cells in lab culture, kisspeptin increased progesterone release.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseProgesterone release
    Study

    catn: not reported in source

    cultured feline ovarian fragments and granulosa cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    10 ng/mlAs given in this study (cat).

    Source sentences

    Summary
    The addition of KISS alone increased proliferation, apoptosis, progesterone, estradiol release, and decreased testosterone but did not affect viability.
    1 context sentence
    Summary · context
    For this purpose, we examined (1) the effect of the addition of BTC (0, 1, 10, and 100 ng/ml) given alone or in combination with KISS (10 ng/ml) on cultured feline ovarian fragments or granulosa cells.
  4. 04LabEx vivo tissueEfficacy outcome

    In cultured feline ovarian cells, KISS alone increased estradiol release.

    In plain wordsIn cat ovarian cells in lab culture, kisspeptin increased estradiol release.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseEstradiol release
    Study

    catn: not reported in source

    cultured feline ovarian fragments and granulosa cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    10 ng/mlAs given in this study (cat).

    Source sentences

    Summary
    The addition of KISS alone increased proliferation, apoptosis, progesterone, estradiol release, and decreased testosterone but did not affect viability.
    1 context sentence
    Summary · context
    For this purpose, we examined (1) the effect of the addition of BTC (0, 1, 10, and 100 ng/ml) given alone or in combination with KISS (10 ng/ml) on cultured feline ovarian fragments or granulosa cells.
  5. 05LabEx vivo tissueEfficacy outcome

    In cultured feline ovarian cells, KISS alone decreased testosterone release.

    In plain wordsIn cat ovarian cells in lab culture, kisspeptin decreased testosterone release.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseTestosterone release
    Study

    catn: not reported in source

    cultured feline ovarian fragments and granulosa cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    10 ng/mlAs given in this study (cat).

    Source sentences

    Summary
    The addition of KISS alone increased proliferation, apoptosis, progesterone, estradiol release, and decreased testosterone but did not affect viability.
    1 context sentence
    Summary · context
    For this purpose, we examined (1) the effect of the addition of BTC (0, 1, 10, and 100 ng/ml) given alone or in combination with KISS (10 ng/ml) on cultured feline ovarian fragments or granulosa cells.
  6. 06LabEx vivo tissueEfficacy outcome

    In cultured feline ovarian cells, KISS alone did not affect viability.

    In plain wordsIn cat ovarian cells in lab culture, kisspeptin did not change cell viability.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeCell viability
    Study

    catn: not reported in source

    cultured feline ovarian fragments and granulosa cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    10 ng/mlAs given in this study (cat).

    Source sentences

    Summary
    The addition of KISS alone increased proliferation, apoptosis, progesterone, estradiol release, and decreased testosterone but did not affect viability.
    1 context sentence
    Summary · context
    For this purpose, we examined (1) the effect of the addition of BTC (0, 1, 10, and 100 ng/ml) given alone or in combination with KISS (10 ng/ml) on cultured feline ovarian fragments or granulosa cells.

Studies that did not test the peptide alone1

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

  1. 07LabNot a test of Kisspeptin-10 aloneEx vivo tissueMechanism

    In cultured feline ovarian cells, BTC mainly inhibited the stimulatory action of KISS on ovarian functions.

    In plain wordsIn cat ovarian cells in lab culture, betacellulin mostly blocked the stimulating effects of kisspeptin.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseEffect of BTC on KISS action
    Study

    catn: not reported in source

    cultured feline ovarian fragments and granulosa cells
    Comparator
    KISS alone
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    Furthermore, BTC mainly inhibited the stimulatory action of KISS on feline ovarian functions.
    1 context sentence
    Summary · context
    For this purpose, we examined (1) the effect of the addition of BTC (0, 1, 10, and 100 ng/ml) given alone or in combination with KISS (10 ng/ml) on cultured feline ovarian fragments or granulosa cells.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.