A nanosystem carrying GYY4137 and TK-SS31 achieved effective drug distribution in the kidney, with pH-responsive H2S release and ROS-responsive SS31 release.
In plain wordsA nanoparticle system with several active parts reached the kidney and released SS31 when reactive oxygen species were present.
- Peptide
- Elamipretide (SS-31)
- Outcome
- Not applicableKidney drug distribution and ROS-responsive SS31 release
- Study
n: not reported in source
- Outcome group
- Pharmacokinetics · Kidney and urinary
Source sentences
The asymmetrical nanosystem achieved effective drug distribution in the kidney as well as pH-responsive hydrogen sulfide (H2S) release and ROS-responsive SS31 release
In this study, Elamipretide (SS-31) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Elamipretide (SS-31).