In a systematic review of treatments for skin photosensitivity in EPP or XLP, controlled trials showed a moderate positive effect of the subcutaneous afamelanotide implant.
In plain wordsIn a review of studies in people with EPP or XLP, trials showed a moderate positive effect of the afamelanotide implant on light sensitivity.
- Peptide
- Melanotan I (afamelanotide)
- Outcome
- Not applicableSkin photosensitivity in EPP or XLP
- Study
n: not reported in source
- Outcome group
- Skin and hair · Skin and wound
- Studied dose
- Dose not stated · subcutaneous implantAs given in this study (human).
Source sentences
the trials showed moderate positive effect of inorganic sunscreen application and subcutaneous implant of afamelanotide
2 context sentences(design, population, supporting numbers)
A total of 40 studies with data on 18 treatment modalities were included.
Of the included studies, 13 were controlled trials.