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Study · Measured the body's own peptide · 2022

2 results

Inverse Correlation of KISS1 and KISS1R Expression in Triple-negative Breast Carcinomas from African American Women.

Qasim M, Ricks-Santi LJ, Naab TJ, Rajack F, Beyene D, Abbas M, Kassim OO, Copeland RL, Kanaan Y

Cancer genomics & proteomics1 Nov 2022Cited by 3 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In breast carcinomas from African American women, KISS1 protein expression was higher in receptor-negative and triple-negative breast cancer than in other subtypes.

    In plain wordsIn breast tumors from African American women, the body's own KISS1 was higher in triple-negative tumors than in other subtypes.

    Outcome
    IncreaseKISS1 protein expression by breast cancer subtype
    Study

    n = 216

    Comparator
    Other breast cancer subtypes
    Outcome group
    Endogenous peptide levels · Cancer

    Source sentences

    Summary
    KISS1 protein expression was found to be higher in receptor-negative and triple-negative breast cancer (TNBC) compared to other subtypes (p<0.001).
    1 context sentence
    Summary · context
    Tissue microarrays were constructed from formalin-fixed, paraffin-embedded surgical blocks from 216 AA patients.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In triple-negative breast carcinomas from African American women, KISS1 and KISS1R expression were inversely correlated.

    In plain wordsIn breast tumors from African American women, the body's own KISS1 level was linked to a lower KISS1R level in triple-negative tumors.

    Outcome
    Not applicableCorrelation of KISS1 and KISS1R expression in triple-negative breast cancer
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Cancer

    Source sentences

    Summary
    Our study showed a significant inverse correlation between KISS1 and KISS1R in TNBC.
    1 context sentence
    Summary · context
    Tissue microarrays were constructed from formalin-fixed, paraffin-embedded surgical blocks from 216 AA patients.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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