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Study · Not a test of the peptide alone · 2022

2 results

An injectable mitochondria-targeted nanodrug loaded-hydrogel for restoring mitochondrial function and hierarchically attenuating oxidative stress to reduce myocardial ischemia-reperfusion injury.

Zhang X, Sun Y, Yang R, Liu B, Liu Y, Yang J, Liu W

Biomaterials28 Jun 2022Cited by 63 (Europe PMC)

PMID35792386 (opens in a new tab)DOI10.1016/j.biomaterials.2022.121656 (opens in a new tab)PepBankPUB-35792386
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Elamipretide (SS-31) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Elamipretide (SS-31).

  1. 01AnimalNot a test of Elamipretide (SS-31) aloneAnimal study (in vivo)Efficacy outcome

    In rats with myocardial ischemia-reperfusion injury, an injectable hydrogel releasing SS31-modified nanomicelles loaded with cyclosporine A restored mitochondrial function.

    In plain wordsIn rats with heart injury after blood flow returned, a hydrogel with SS31 micelles and cyclosporine A restored mitochondrial function.

    Peptide
    Elamipretide (SS-31)
    Outcome
    IncreaseMitochondrial function
    Study

    ratn: not reported in source

    Myocardial ischemia-reperfusion injury
    Outcome group
    Mitochondrial function · Cardiovascular

    Source sentences

    Summary
    In rat model of myocardial I/R injury with administration of this injectable hydrogel, the targeted release of PTPSCs efficiently restores mitochondrial and cardiac function.

    In this study, Elamipretide (SS-31) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Elamipretide (SS-31).

  2. 02AnimalNot a test of Elamipretide (SS-31) aloneAnimal study (in vivo)Efficacy outcome

    In rats with myocardial ischemia-reperfusion injury, an injectable hydrogel releasing SS31-modified nanomicelles loaded with cyclosporine A restored cardiac function.

    In plain wordsIn rats with heart injury after blood flow returned, a hydrogel with SS31 micelles and cyclosporine A restored heart function.

    Peptide
    Elamipretide (SS-31)
    Outcome
    IncreaseCardiac function
    Study

    ratn: not reported in source

    Myocardial ischemia-reperfusion injury
    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    In rat model of myocardial I/R injury with administration of this injectable hydrogel, the targeted release of PTPSCs efficiently restores mitochondrial and cardiac function.

    In this study, Elamipretide (SS-31) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Elamipretide (SS-31).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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