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Study · Measured the body's own peptide · 2020

1 result

Thymosin β4 cytoplasmic/nuclear translocation as a new marker of cellular stress. A Caco2 case study.

Coni P, Piras M, Mateddu A, Piludu M, Orru G, Scano A, Cabras T, Piras V, Lachowicz JI, Jaremko M, Jaremko M, Faa G, Castagnola M, Pichiri G

RSC advances30 Mar 2020Cited by 9 (Europe PMC)

PMID35497634 (opens in a new tab)PMCIDPMC9051466 (opens in a new tab)DOI10.1039/c9ra10365a (opens in a new tab)PepBankPUB-35497634
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In Caco2 cells, different stress inducers led to a similar cytoplasmic/nuclear translocation of Tβ4.

    In plain wordsIn cells, different stress triggers moved the cell's own Tβ4 between the cytoplasm and the nucleus in a similar way.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableTβ4 cytoplasmic/nuclear translocation under cellular stress
    Study

    humann: not reported in source

    Caco2 colon adenocarcinoma cells
    Outcome group
    Oxidative stress · Whole body

    Source sentences

    Summary
    different stress inducers lead to a similar Tβ4 cytoplasmic/nuclear translocation.
    1 context sentence
    Summary · context
    We addressed the relevance of Tβ4 in cellular stress conditions by using different treatments (serum starvation, DMSO, and butyrate administration) in a colon adenocarcinoma cell line (CaCo2), a cell line frequently used for in vitro experimental studies of Tβ4.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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